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Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes
Special AT-rich binding protein-1 (SATB1) integrates higher-order chromatin architecture with gene regulation, thereby regulating multiple signaling pathways. In mammalian cells SATB1 directly interacts with β-catenin and regulates the expression of Wnt targets by binding to their promoters. Whether...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873079/ https://www.ncbi.nlm.nih.gov/pubmed/33564000 http://dx.doi.org/10.1038/s41598-021-81324-2 |