Cargando…

Intranasal Insulin for Alzheimer’s Disease

Brain insulin signaling contributes to memory function and might be a viable target in the prevention and treatment of memory impairments including Alzheimer’s disease. This short narrative review explores the potential of central nervous system (CNS) insulin administration via the intranasal pathwa...

Descripción completa

Detalles Bibliográficos
Autor principal:	Hallschmid, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873098/ https://www.ncbi.nlm.nih.gov/pubmed/33515428 http://dx.doi.org/10.1007/s40263-020-00781-x

Ejemplares similares

Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
por: Freiherr, Jessica, et al.
Publicado: (2013)

Postprandial Administration of Intranasal Insulin Intensifies Satiety and Reduces Intake of Palatable Snacks in Women
por: Hallschmid, Manfred, et al.
Publicado: (2012)

Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men
por: Benedict, Christian, et al.
Publicado: (2011)

Metabolic and Cognitive Outcomes of Subchronic Once-Daily Intranasal Insulin Administration in Healthy Men
por: Ritze, Yvonne, et al.
Publicado: (2018)

Intranasal insulin in Alzheimer’s disease: Food for thought
por: Chapman, Colin D., et al.
Publicado: (2018)

Intranasal Insulin Suppresses Food Intake via Enhancement of Brain Energy Levels in Humans
por: Jauch-Chara, Kamila, et al.
Publicado: (2012)

Intranasal Treatment of Central Nervous System Dysfunction in Humans
por: Chapman, Colin D., et al.
Publicado: (2012)

The effect of intranasal insulin on appetite and mood in women with and without obesity: an experimental medicine study
por: Schneider, Elizabeth, et al.
Publicado: (2022)

Safety and efficacy of intranasal insulin in patients with Alzheimer’s disease: a systematic review and meta-analysis
por: AboEl-Azm, Yosra Hussein, et al.
Publicado: (2023)

Intranasal rifampicin for Alzheimer's disease prevention
por: Umeda, Tomohiro, et al.
Publicado: (2018)

Central Nervous Insulin Administration before Nocturnal Sleep Decreases Breakfast Intake in Healthy Young and Elderly Subjects
por: Santiago, João C. P., et al.
Publicado: (2017)

Distinct and Convergent Beneficial Effects of Estrogen and Insulin on Cognitive Function in Healthy Young Men
por: Krug, Rosemarie, et al.
Publicado: (2021)

Insulin and Insulin Resistance in Alzheimer’s Disease
por: Sędzikowska, Aleksandra, et al.
Publicado: (2021)

Intranasal insulin modulates cerebrospinal fluid markers of neuroinflammation in mild cognitive impairment and Alzheimer’s disease: a randomized trial
por: Kellar, Derek, et al.
Publicado: (2022)

Intranasal insulin neuroprotection in ischemic stroke
por: Lioutas, Vasileios-Arsenios, et al.
Publicado: (2016)

The role of insulin sensitivity and intranasally applied insulin on olfactory perception
por: Edwin Thanarajah, Sharmili, et al.
Publicado: (2019)

Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease
por: Fihurka, Oksana, et al.
Publicado: (2023)

Intranasal Drug Administration in Alzheimer-Type Dementia: Towards Clinical Applications
por: Taléns-Visconti, Raquel, et al.
Publicado: (2023)

Intranasal Insulin Ameliorates Experimental Diabetic Neuropathy
por: Francis, George, et al.
Publicado: (2009)

Targeting Mediators of Smoking Persistence with Intranasal Insulin
por: Hamidovic, Ajna
Publicado: (2017)

The Rationale for Insulin Therapy in Alzheimer’s Disease
por: Ribarič, Samo
Publicado: (2016)

Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence?
por: Stanley, Molly, et al.
Publicado: (2016)

Central Nervous Insulin Signaling in Sleep-Associated Memory Formation and Neuroendocrine Regulation
por: Feld, Gordon B, et al.
Publicado: (2016)

Intranasal Insulin Reduces White Matter Hyperintensity Progression in Association with Improvements in Cognition and CSF Biomarker Profiles in Mild Cognitive Impairment and Alzheimer’s Disease
por: Kellar, D., et al.
Publicado: (2021)

Intranasal Dantrolene as a Disease-Modifying Drug in Alzheimer 5XFAD Mice
por: Shi, Yun, et al.
Publicado: (2020)

Euglycemic Infusion of Insulin Detemir Compared With Human Insulin Appears to Increase Direct Current Brain Potential Response and Reduces Food Intake While Inducing Similar Systemic Effects
por: Hallschmid, Manfred, et al.
Publicado: (2010)

Insulin Resistance and Diabetes Mellitus in Alzheimer’s Disease
por: Burillo, Jesús, et al.
Publicado: (2021)

Shortcut Approaches to Substance Delivery into the Brain Based on Intranasal Administration Using Nanodelivery Strategies for Insulin
por: Tashima, Toshihiko
Publicado: (2020)

Distribution of insulin in trigeminal nerve and brain after intranasal administration
por: Lochhead, Jeffrey J., et al.
Publicado: (2019)

Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer’s Disease-like Neuropathology in a Mouse Model for Down Syndrome
por: Tramutola, Antonella, et al.
Publicado: (2023)

Rapid transport of insulin to the brain following intranasal administration in rats
por: Fan, Lir-Wan, et al.
Publicado: (2019)

Mechanisms of Intranasal Deferoxamine in Neurodegenerative and Neurovascular Disease
por: Kosyakovsky, Jacob, et al.
Publicado: (2021)

Intranasal administration of dauricine loaded on graphene oxide: multi-target therapy for Alzheimer's disease
por: Wang, Kaixuan, et al.
Publicado: (2021)

Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database
por: Lehrer, Steven, et al.
Publicado: (2018)

A sweet spot for the sleeping brain: Linking human sleep physiology and glucoregulation
por: Niethard, Niels, et al.
Publicado: (2023)

Current Insights on the Use of Insulin and the Potential Use of Insulin Mimetics in Targeting Insulin Signalling in Alzheimer’s Disease
por: Woodfield, Amy, et al.
Publicado: (2022)

Enhancement of Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
por: Novak, Vera, et al.
Publicado: (2014)

Odor Sensitivity After Intranasal Insulin Application Is Modulated by Gender
por: Rodriguez-Raecke, Rea, et al.
Publicado: (2018)

Intranasal Insulin Administration to Prevent Delayed Neurocognitive Recovery and Postoperative Neurocognitive Disorder: A Narrative Review
por: Badenes, Rafael, et al.
Publicado: (2021)

How Can Insulin Resistance Cause Alzheimer’s Disease?
por: Yoon, Ji Hye, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1h8sdtjearkh4710acotiqbiv6