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The association between plant-based dietary patterns and risk of breast cancer: a case–control study
Limited data are available, linking the plant-based diets to breast cancer (BC). We examined the association of overall plant-based diet index (PDI), hypothesized healthful (hPDI) and unhealthful versions of a plant-based diet index (uPDI) with BC in Iranian women. This population-based case–control...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873223/ https://www.ncbi.nlm.nih.gov/pubmed/33564027 http://dx.doi.org/10.1038/s41598-021-82659-6 |
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author | Rigi, Somaye Mousavi, Seyed Mohammad Benisi-Kohansal, Sanaz Azadbakht, Leila Esmaillzadeh, Ahmad |
author_facet | Rigi, Somaye Mousavi, Seyed Mohammad Benisi-Kohansal, Sanaz Azadbakht, Leila Esmaillzadeh, Ahmad |
author_sort | Rigi, Somaye |
collection | PubMed |
description | Limited data are available, linking the plant-based diets to breast cancer (BC). We examined the association of overall plant-based diet index (PDI), hypothesized healthful (hPDI) and unhealthful versions of a plant-based diet index (uPDI) with BC in Iranian women. This population-based case–control study included 350 cases with newly diagnosed BC and 700 age-matched apparently healthy controls. We collected dietary data using a validated, Willett-format semi-quantitative food frequency questionnaire. Using these data, we generated a PDI by dedicating positive scores to plant foods, and reverse scores to animal foods, hPDI by assigning positive scores to healthy plant foods and reverse scores to less healthy plant foods and animal foods, and finally uPDI in which positive scores were assigned to less healthy plant foods and reverse scores to healthy plant foods and animal foods. After controlling for potential confounders, individuals in the highest quartile of PDI had 67% lower odds of BC than those in the lowest quartile (OR 0.33; 95% CI 0.22–0.50). Individuals with the greatest adherence to hPDI were 36% less likely to have BC than those with the lowest adherence, in the fully adjusted model (OR 0.64; 95% CI 0.43–0.94). In terms of uPDI, women in the top quartile had a 2.23 times greater chance of BC than those in the bottom quartile (OR 2.23; 95% CI 1.48–3.36). Greater adherence to PDI and hPDI was inversely associated with the risk of BC, whereas uPDI was associated with an increased risk. |
format | Online Article Text |
id | pubmed-7873223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-78732232021-02-11 The association between plant-based dietary patterns and risk of breast cancer: a case–control study Rigi, Somaye Mousavi, Seyed Mohammad Benisi-Kohansal, Sanaz Azadbakht, Leila Esmaillzadeh, Ahmad Sci Rep Article Limited data are available, linking the plant-based diets to breast cancer (BC). We examined the association of overall plant-based diet index (PDI), hypothesized healthful (hPDI) and unhealthful versions of a plant-based diet index (uPDI) with BC in Iranian women. This population-based case–control study included 350 cases with newly diagnosed BC and 700 age-matched apparently healthy controls. We collected dietary data using a validated, Willett-format semi-quantitative food frequency questionnaire. Using these data, we generated a PDI by dedicating positive scores to plant foods, and reverse scores to animal foods, hPDI by assigning positive scores to healthy plant foods and reverse scores to less healthy plant foods and animal foods, and finally uPDI in which positive scores were assigned to less healthy plant foods and reverse scores to healthy plant foods and animal foods. After controlling for potential confounders, individuals in the highest quartile of PDI had 67% lower odds of BC than those in the lowest quartile (OR 0.33; 95% CI 0.22–0.50). Individuals with the greatest adherence to hPDI were 36% less likely to have BC than those with the lowest adherence, in the fully adjusted model (OR 0.64; 95% CI 0.43–0.94). In terms of uPDI, women in the top quartile had a 2.23 times greater chance of BC than those in the bottom quartile (OR 2.23; 95% CI 1.48–3.36). Greater adherence to PDI and hPDI was inversely associated with the risk of BC, whereas uPDI was associated with an increased risk. Nature Publishing Group UK 2021-02-09 /pmc/articles/PMC7873223/ /pubmed/33564027 http://dx.doi.org/10.1038/s41598-021-82659-6 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Rigi, Somaye Mousavi, Seyed Mohammad Benisi-Kohansal, Sanaz Azadbakht, Leila Esmaillzadeh, Ahmad The association between plant-based dietary patterns and risk of breast cancer: a case–control study |
title | The association between plant-based dietary patterns and risk of breast cancer: a case–control study |
title_full | The association between plant-based dietary patterns and risk of breast cancer: a case–control study |
title_fullStr | The association between plant-based dietary patterns and risk of breast cancer: a case–control study |
title_full_unstemmed | The association between plant-based dietary patterns and risk of breast cancer: a case–control study |
title_short | The association between plant-based dietary patterns and risk of breast cancer: a case–control study |
title_sort | association between plant-based dietary patterns and risk of breast cancer: a case–control study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873223/ https://www.ncbi.nlm.nih.gov/pubmed/33564027 http://dx.doi.org/10.1038/s41598-021-82659-6 |
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