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Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy
Polycomb repressive complex 1 (PRC1) is an essential chromatin-based repressor of gene transcription. How PRC1 engages with chromatin to identify its target genes and achieve gene repression remains poorly defined, representing a major hurdle to our understanding of Polycomb system function. Here, w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873255/ https://www.ncbi.nlm.nih.gov/pubmed/33563969 http://dx.doi.org/10.1038/s41467-021-21130-6 |