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Histone deacetylase inhibitors suppress ACE2 and ABO simultaneously, suggesting a preventive potential against COVID-19

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide as a pandemic throughout 2020. Since the virus uses angiotensin-converting enzyme 2 (ACE2) as a receptor for cellular entry, increment of ACE2 would lead to an increased ri...

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Detalles Bibliográficos
Autores principales: Takahashi, Yoichiro, Hayakawa, Akira, Sano, Rie, Fukuda, Haruki, Harada, Megumi, Kubo, Rieko, Okawa, Takafumi, Kominato, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873266/
https://www.ncbi.nlm.nih.gov/pubmed/33564039
http://dx.doi.org/10.1038/s41598-021-82970-2