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Phase 1 open-label study of panobinostat, lenalidomide, bortezomib + dexamethasone in relapsed and relapsed/refractory multiple myeloma

Additional therapeutic options are needed for relapsed and refractory multiple myeloma (RRMM). We present data from a phase 1b, open-label, dose-escalation study (NCT01965353) of 20 patients with RRMM (median age: 63 years [range: 50–77]) and a median of four prior regimens (range: 2–14); 85% had re...

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Detalles Bibliográficos
Autores principales:	Laubach, Jacob P., Tuchman, Sascha A., Rosenblatt, Jacalyn M., Mitsiades, Constantine S., Colson, Kathleen, Masone, Kelly, Warren, Diane, Redd, Robert A., Grayson, Dena, Richardson, Paul G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873303/ https://www.ncbi.nlm.nih.gov/pubmed/33563894 http://dx.doi.org/10.1038/s41408-021-00407-5

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