More Insights on the Use of γ‐Secretase Inhibitors in Cancer Treatment

The NOTCH1 gene encodes a transmembrane receptor protein with activating mutations observed in many T‐cell acute lymphoblastic leukemias (T‐ALLs) and lymphomas, as well as in other tumor types, which has led to interest in inhibiting NOTCH1 signaling as a therapeutic target in cancer. Several classe...

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Detalles Bibliográficos
Autores principales: López‐Nieva, Pilar, González‐Sánchez, Laura, Cobos‐Fernández, María Ángeles, Córdoba, Raúl, Santos, Javier, Fernández‐Piqueras, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Hematologic Malignancies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873333/
https://www.ncbi.nlm.nih.gov/pubmed/33191568
http://dx.doi.org/10.1002/onco.13595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873333/
https://www.ncbi.nlm.nih.gov/pubmed/33191568
http://dx.doi.org/10.1002/onco.13595

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