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Population pharmacokinetics of vedolizumab in Asian and non-Asian patients with ulcerative colitis and Crohn’s disease

BACKGROUND/AIMS: Vedolizumab is indicated for moderately-to-severely active ulcerative colitis (UC) and Crohn’s disease (CD). Because multiple factors may result in different pharmacokinetics and clinical efficacies, understanding determinants of vedolizumab clearance may enhance dose and treatment...

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Detalles Bibliográficos
Autores principales: Okamoto, Hiroyuki, Dirks, Nathanael L., Rosario, Maria, Hori, Tetsuharu, Hibi, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873400/
https://www.ncbi.nlm.nih.gov/pubmed/32635680
http://dx.doi.org/10.5217/ir.2019.09167

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