Cargando…
Endoscopic molecular imaging in inflammatory bowel disease
Molecular imaging is a technique for imaging the processes occurring in a living body at a molecular level in real-time, combining molecular cell biology with advanced imaging technologies using molecular probes and fluorescence. Gastrointestinal endoscopic molecular imaging shows great promise for...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association for the Study of Intestinal Diseases
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873406/ https://www.ncbi.nlm.nih.gov/pubmed/32299156 http://dx.doi.org/10.5217/ir.2019.09175 |
_version_ | 1783649377923891200 |
---|---|
author | Ham, Nam Seok Myung, Seung-Jae |
author_facet | Ham, Nam Seok Myung, Seung-Jae |
author_sort | Ham, Nam Seok |
collection | PubMed |
description | Molecular imaging is a technique for imaging the processes occurring in a living body at a molecular level in real-time, combining molecular cell biology with advanced imaging technologies using molecular probes and fluorescence. Gastrointestinal endoscopic molecular imaging shows great promise for improving the identification of neoplasms, providing characterization for patient stratification and assessing the response to molecular targeted therapy. In inflammatory bowel disease, endoscopic molecular imaging can be used to assess disease severity and predict therapeutic response and prognosis. Endoscopic molecular imaging is also able to visualize dysplasia in the presence of background inflammation. Several preclinical and clinical trials have evaluated endoscopic molecular imaging; however, this area is just beginning to evolve, and many issues have not been solved yet. In the future, it is expected that endoscopic molecular imaging will be of increasing interest among clinicians as a new technology for the identification and evaluation of colorectal neoplasm and colitis-associated cancer. |
format | Online Article Text |
id | pubmed-7873406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Association for the Study of Intestinal Diseases |
record_format | MEDLINE/PubMed |
spelling | pubmed-78734062021-02-18 Endoscopic molecular imaging in inflammatory bowel disease Ham, Nam Seok Myung, Seung-Jae Intest Res Review Molecular imaging is a technique for imaging the processes occurring in a living body at a molecular level in real-time, combining molecular cell biology with advanced imaging technologies using molecular probes and fluorescence. Gastrointestinal endoscopic molecular imaging shows great promise for improving the identification of neoplasms, providing characterization for patient stratification and assessing the response to molecular targeted therapy. In inflammatory bowel disease, endoscopic molecular imaging can be used to assess disease severity and predict therapeutic response and prognosis. Endoscopic molecular imaging is also able to visualize dysplasia in the presence of background inflammation. Several preclinical and clinical trials have evaluated endoscopic molecular imaging; however, this area is just beginning to evolve, and many issues have not been solved yet. In the future, it is expected that endoscopic molecular imaging will be of increasing interest among clinicians as a new technology for the identification and evaluation of colorectal neoplasm and colitis-associated cancer. Korean Association for the Study of Intestinal Diseases 2021-01 2020-04-20 /pmc/articles/PMC7873406/ /pubmed/32299156 http://dx.doi.org/10.5217/ir.2019.09175 Text en © Copyright 2021. Korean Association for the Study of Intestinal Diseases. All rights reserved. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Ham, Nam Seok Myung, Seung-Jae Endoscopic molecular imaging in inflammatory bowel disease |
title | Endoscopic molecular imaging in inflammatory bowel disease |
title_full | Endoscopic molecular imaging in inflammatory bowel disease |
title_fullStr | Endoscopic molecular imaging in inflammatory bowel disease |
title_full_unstemmed | Endoscopic molecular imaging in inflammatory bowel disease |
title_short | Endoscopic molecular imaging in inflammatory bowel disease |
title_sort | endoscopic molecular imaging in inflammatory bowel disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873406/ https://www.ncbi.nlm.nih.gov/pubmed/32299156 http://dx.doi.org/10.5217/ir.2019.09175 |
work_keys_str_mv | AT hamnamseok endoscopicmolecularimagingininflammatoryboweldisease AT myungseungjae endoscopicmolecularimagingininflammatoryboweldisease |