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Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing

OBJECTIVE: Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular and cellular heterogeneity in GA using single-cell RNA sequencing (scRNA-seq). DESIGN: We performe...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Hu, Shuofeng, Min, Min, Ni, Yanli, Lu, Zheng, Sun, Xiaotian, Wu, Jiaqi, Liu, Bing, Ying, Xiaomin, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873416/
https://www.ncbi.nlm.nih.gov/pubmed/32532891
http://dx.doi.org/10.1136/gutjnl-2019-320368