A Prospective Controlled Trial to Evaluate Safety and Efficacy of in vitro Expanded Recipient Regulatory T Cell Therapy and Tocilizumab Together With Donor Bone Marrow Infusion in HLA-Mismatched Living Donor Kidney Transplant Recipients (Trex001)

Background: The induction of donor-specific immunological tolerance could improve outcome after kidney transplantation. However, no tolerance protocol is available for routine clinical use. Chimerism-based regimens hold promise, but their widespread application is impeded in part by unresolved safet...

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Detalles Bibliográficos
Autores principales: Oberbauer, Rainer, Edinger, Matthias, Berlakovich, Gabriela, Kalhs, Peter, Worel, Nina, Heinze, Georg, Wolzt, Michael, Lion, Thomas, Wekerle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873436/
https://www.ncbi.nlm.nih.gov/pubmed/33585521
http://dx.doi.org/10.3389/fmed.2020.634260

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