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Comparison of Islet Characterization from Use of Standard Crude Collagenase to GMP-Grade Collagenase Enzyme Blends in Preweaned Porcine Islet Isolations
For the advancement of porcine xenotransplantation for clinical use in type 1 diabetes mellitus, the concerns of a sustainable and safe digestion enzyme blend must be overcome. Incorporating good manufacturing practices (GMP) can facilitate this through utilizing GMP-grade enzymes. In conjunction, s...
Autores principales: | Corrales, Nicole, Park, Soomin, Lau, Hien, Xu, Ivana, Luong, Colleen, Rodriguez, Samuel, Mönch, Johanna, Alexander, Michael, Lakey, Jonathan RT |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873766/ https://www.ncbi.nlm.nih.gov/pubmed/33267618 http://dx.doi.org/10.1177/0963689720977835 |
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