Cargando…

Single-Cell Analysis Reveals Characterization of Infiltrating T Cells in Moderately Differentiated Colorectal Cancer

OBJECTIVE: This study aimed to characterize the tumor-infiltrating T cells in moderately differentiated colorectal cancer. METHODS: Using single-cell RNA sequencing data of isolated 1632 T cells from tumor tissue and 1252 T cells from the peripheral blood of CRC patients, unsupervised clustering ana...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Xi, Qi, Quan, Pan, Yuefen, Zhou, Qing, Wu, Yinhang, Zhuang, Jing, Xu, Jiamin, Pan, Mingyue, Han, Shuwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873865/ https://www.ncbi.nlm.nih.gov/pubmed/33584715 http://dx.doi.org/10.3389/fimmu.2020.620196

Ejemplares similares

Colorectal cancer and gut viruses: a visualized analysis based on CiteSpace knowledge graph
por: Jian, Chu, et al.
Publicado: (2023)

Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer
por: Xi, Yang, et al.
Publicado: (2019)

Advances in immunotyping of colorectal cancer
por: Wu, Yinhang, et al.
Publicado: (2023)

Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer
por: Yan, Zhang, et al.
Publicado: (2022)

Immune-related genes in tumor-specific CD4(+) and CD8(+) T cells in colon cancer
por: Yang, Xi, et al.
Publicado: (2020)

Screening of T Cell-Related Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks in Non-Small-Cell Lung Cancer
por: Duan, Jinlong, et al.
Publicado: (2020)

Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer?
por: Shuwen, Han, et al.
Publicado: (2017)

Inhibitory effect of sodium butyrate on colorectal cancer cells and construction of the related molecular network
por: Xi, Yang, et al.
Publicado: (2021)

Different Characteristics in Gut Microbiome between Advanced Adenoma Patients and Colorectal Cancer Patients by Metagenomic Analysis
por: Han, Shuwen, et al.
Publicado: (2022)

Progress in Research on Colorectal Cancer-Related Microorganisms and Metabolites
por: Han, Shuwen, et al.
Publicado: (2020)

Prognostic model based on six PD-1 expression and immune infiltration-associated genes predicts survival in breast cancer
por: Junjun, Shen, et al.
Publicado: (2022)

Black Raspberries Enhance Natural Killer Cell Infiltration into the Colon and Suppress the Progression of Colorectal Cancer
por: Pan, Pan, et al.
Publicado: (2017)

Single-cell transcriptome analysis reveals T population heterogeneity and functions in tumor microenvironment of colorectal cancer metastases
por: Zhuang, Jing, et al.
Publicado: (2023)

Baseline Peripheral Blood Leukocytosis Is Negatively Correlated With T-Cell Infiltration Predicting Worse Outcome in Colorectal Cancers
por: Hu, Xiang, et al.
Publicado: (2018)

Endostatin induces normalization of blood vessels in colorectal cancer and promotes infiltration of CD8+ T cells to improve anti-PD-L1 immunotherapy
por: Chu, Xiao-Dong, et al.
Publicado: (2022)

Profiles of Immune Cell Infiltration in Carotid Artery Atherosclerosis Based on Gene Expression Data
por: Wang, Long, et al.
Publicado: (2021)

Tumor-Infiltrating Immune Cells Act as a Marker for Prognosis in Colorectal Cancer
por: Ye, Lele, et al.
Publicado: (2019)

Potential screening and early diagnosis method for cancer: Tongue diagnosis
por: HAN, SHUWEN, et al.
Publicado: (2016)

Immune-infiltrating signature-based classification reveals CD103(+)CD39(+) T cells associate with colorectal cancer prognosis and response to immunotherapy
por: Luo, Yang, et al.
Publicado: (2022)

Physical Characterization of Colorectal Cancer Spheroids and Evaluation of NK Cell Infiltration Through a Flow-Based Analysis
por: Sargenti, Azzurra, et al.
Publicado: (2020)

Aging characteristics of colorectal cancer based on gut microbiota
por: Wu, Yinhang, et al.
Publicado: (2023)

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
por: Toor, Salman M., et al.
Publicado: (2016)

Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting
por: Aristin Revilla, Sonia, et al.
Publicado: (2022)

Identification of hub biomarkers and immune cell infiltration characteristics of polymyositis by bioinformatics analysis
por: Jia, Qi, et al.
Publicado: (2022)

Immune Checkpoints in Circulating and Tumor-Infiltrating CD4(+) T Cell Subsets in Colorectal Cancer Patients
por: Toor, Salman M., et al.
Publicado: (2019)

Identification of Immune Cell Infiltration and Immune-Related Genes in the Tumor Microenvironment of Glioblastomas
por: Huang, Sicong, et al.
Publicado: (2020)

Identification of immune infiltration and cuproptosis-related subgroups in Crohn’s disease
por: Yuan, Yifan, et al.
Publicado: (2022)

ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer
por: Shen, Xiaonan, et al.
Publicado: (2022)

Revealing the Immune Infiltration Landscape and Identifying Diagnostic Biomarkers for Lumbar Disc Herniation
por: Wang, Linbang, et al.
Publicado: (2021)

Combination of single-cell and bulk RNA seq reveals the immune infiltration landscape and targeted therapeutic drugs in spinal cord injury
por: Zhang, Qing, et al.
Publicado: (2023)

Screening of molecular targets and construction of a ceRNA network for oxaliplatin resistance in colorectal cancer
por: Wei, Wu, et al.
Publicado: (2019)

Characterization of the immune cell infiltration landscape in myxofibrosarcoma to aid immunotherapy
por: Zhao, Zi-Yue, et al.
Publicado: (2022)

Using whole-genome sequencing (WGS) to plot colorectal cancer-related gut microbiota in a population with varied geography
por: Shuwen, Han, et al.
Publicado: (2022)

Transcriptome Analysis of Bronchoalveolar Lavage Fluid From Children With Mycoplasma pneumoniae Pneumonia Reveals Natural Killer and T Cell-Proliferation Responses
por: Gao, Man, et al.
Publicado: (2018)

Identification of B cell marker genes based on single-cell sequencing to establish a prognostic model and identify immune infiltration in osteosarcoma
por: Zhang, Zhongmin, et al.
Publicado: (2022)

Analysis of Bulk RNA Sequencing Data Reveals Novel Transcription Factors Associated With Immune Infiltration Among Multiple Cancers
por: Liu, Lei, et al.
Publicado: (2021)

Characterization of Different Subtypes of Immune Cell Infiltration in Glioblastoma to Aid Immunotherapy
por: Feng, Peng, et al.
Publicado: (2022)

m5C regulator-mediated modification patterns and tumor microenvironment infiltration characterization in colorectal cancer: One step closer to precision medicine
por: Chen, Baoxiang, et al.
Publicado: (2022)

Novel Immune Infiltrating Cell Signature Based on Cell Pair Algorithm Is a Prognostic Marker in Cancer
por: Zhang, Hao, et al.
Publicado: (2021)

Identification of necroptosis-related subtypes, development of a novel signature, and characterization of immune infiltration in colorectal cancer
por: Sun, Mengyu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s6mrtog5vis7i4stkp6g10eiao