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How Well Can Multivariate and Univariate GWAS Distinguish Between True and Spurious Pleiotropy?

Quantification of the simultaneous contributions of loci to multiple traits, a phenomenon called pleiotropy, is facilitated by the increased availability of high-throughput genotypic and phenotypic data. To understand the prevalence and nature of pleiotropy, the ability of multivariate and univariat...

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Detalles Bibliográficos
Autores principales: Fernandes, Samuel B., Zhang, Kevin S., Jamann, Tiffany M., Lipka, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873880/
https://www.ncbi.nlm.nih.gov/pubmed/33584799
http://dx.doi.org/10.3389/fgene.2020.602526

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