Cargando…
How Well Can Multivariate and Univariate GWAS Distinguish Between True and Spurious Pleiotropy?
Quantification of the simultaneous contributions of loci to multiple traits, a phenomenon called pleiotropy, is facilitated by the increased availability of high-throughput genotypic and phenotypic data. To understand the prevalence and nature of pleiotropy, the ability of multivariate and univariat...
Autores principales: | Fernandes, Samuel B., Zhang, Kevin S., Jamann, Tiffany M., Lipka, Alexander E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873880/ https://www.ncbi.nlm.nih.gov/pubmed/33584799 http://dx.doi.org/10.3389/fgene.2020.602526 |
Ejemplares similares
-
Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation
por: Smith, Courtney J, et al.
Publicado: (2022) -
Univariate and Multivariate QTL Analyses Reveal Covariance Among Mineral Elements in the Rice Ionome
por: Liu, Huan, et al.
Publicado: (2021) -
Comparison of F-tests for Univariate and Multivariate Mixed-Effect Models in Genome-Wide Association Mapping
por: Onogi, Akio
Publicado: (2019) -
MetaPhat: Detecting and Decomposing Multivariate Associations From Univariate Genome-Wide Association Statistics
por: Lin, Jake, et al.
Publicado: (2020) -
Univariable and Multivariable Two-Sample Mendelian Randomization Investigating the Effects of Leisure Sedentary Behaviors on the Risk of Lung Cancer
por: Peng, Haoxin, et al.
Publicado: (2021)