Piperazine-Derived α(1D/1A) Antagonist 1- Benzyl-N- (3-(4- (2-Methoxyphenyl) Piperazine-1-yl) Propyl) -1H- Indole-2- Carboxamide Induces Apoptosis in Benign Prostatic Hyperplasia Independently of α1-Adrenoceptor Blocking

Previous studies have indicated that α(1D/1A) antagonist naftopidil (NAF) suppresses prostate growth by decreasing cell proliferation without affecting apoptosis and prostate volume in benign prostatic hyperplasia (BPH). A NAF-derived α1D/1A antagonist 1- benzyl-N-(3-(4-(2-methoxyphenyl) piperazine-...

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Detalles Bibliográficos
Autores principales: Xiao, Qing, Liu, Qi-Meng, Jiang, Ru-Chao, Chen, Kai-Feng, Zhu, Xiang, Ma, Lei, Li, Wei-Xi, He, Fei, Huang, Jun-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7873900/
https://www.ncbi.nlm.nih.gov/pubmed/33584271
http://dx.doi.org/10.3389/fphar.2020.594038

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