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A Review of Statistical Methods for Identifying Trait-Relevant Tissues and Cell Types

Genome-wide association studies (GWASs) have identified and replicated many genetic variants that are associated with diseases and disease-related complex traits. However, the biological mechanisms underlying these identified associations remain largely elusive. Exploring the biological mechanisms u...

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Detalles Bibliográficos
Autores principales: Zhu, Huanhuan, Shang, Lulu, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874162/
https://www.ncbi.nlm.nih.gov/pubmed/33584792
http://dx.doi.org/10.3389/fgene.2020.587887