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Irradiated Tumor Fibroblasts Avoid Immune Recognition and Retain Immunosuppressive Functions Over Natural Killer Cells

Recent studies have demonstrated that radiotherapy is able to induce anti-tumor immune responses in addition to mediating direct cytotoxic effects. Cancer-associated fibroblasts (CAFs) are central constituents of the tumor stroma and participate actively in tumor immunoregulation. However, the capac...

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Detalles Bibliográficos
Autores principales: Yang, Nannan, Lode, Kristin, Berzaghi, Rodrigo, Islam, Ashraful, Martinez-Zubiaurre, Inigo, Hellevik, Turid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874190/
https://www.ncbi.nlm.nih.gov/pubmed/33584669
http://dx.doi.org/10.3389/fimmu.2020.602530