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Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa

The carbohydrate-binding protein LecA (PA-IL) from Pseudomonas aeruginosa plays an important role in the formation of biofilms in chronic infections. Development of inhibitors to disrupt LecA-mediated biofilms is desired but it is limited to carbohydrate-based ligands. Moreover, discovery of drug-li...

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Detalles Bibliográficos
Autores principales:	Shanina, Elena, Siebs, Eike, Zhang, Hengxi, Varón Silva, Daniel, Joachim, Ines, Titz, Alexander, Rademacher, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874386/ https://www.ncbi.nlm.nih.gov/pubmed/32573695 http://dx.doi.org/10.1093/glycob/cwaa057

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