Cargando…

Coexisting flavonoids and administration route effect on pharmacokinetics of Puerarin in MCAO rats

A pharmacokinetic comparison was made to evaluate the influence from other components in the Radix Puerariae Extract on pharmacokinetic behavior of Puerarin. Samples of blood and brain were collected by microdialysis and determined by high-performance liquid chromatography–mass spectrometry (MS)/MS....

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Pengyue, Zhong, Linying, Yang, Linjie, Bai, Jie, Lu, Yang, Du, Shouying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874534/ https://www.ncbi.nlm.nih.gov/pubmed/33817233 http://dx.doi.org/10.1515/biol-2020-0053

Ejemplares similares

Bioavailability and Brain-Targeting of Geniposide in Gardenia-Borneol Co-Compound by Different Administration Routes in Mice
por: Lu, Yang, et al.
Publicado: (2012)

Effects of puerarin on the pharmacokinetics of triptolide in rats
por: Wang, Qingfa, et al.
Publicado: (2019)

Development of a MD-LC-MS/MS Method to Analyze 3 Bioactive Compounds in Huoxuezhitong Rubber Patch and Application to a Pharmacokinetic Study in Rats
por: Cui, Yahua, et al.
Publicado: (2019)

Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin
por: Zhang, Guozhe, et al.
Publicado: (2020)

Metabolic profile of puerarin in rats after intragastric administration of puerarin solid lipid nanoparticles
por: Luo, Cheng-Feng, et al.
Publicado: (2013)

Comparison of MSC-Neurogenin1 administration modality in MCAO rat model
por: Shin, Dong Hoon, et al.
Publicado: (2016)

Pharmacological Activity, Pharmacokinetics, and Clinical Research Progress of Puerarin
por: Wang, Di, et al.
Publicado: (2022)

White Pepper and Piperine Have Different Effects on Pharmacokinetics of Puerarin in Rats
por: Liang, Yong-Zhuo, et al.
Publicado: (2014)

Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism
por: Zhang, Huan, et al.
Publicado: (2020)

Comparative pharmacokinetics of four major compounds after oral administration of Mori Cortex total flavonoid extract in normal and diabetic rats
por: Xiong, Shan, et al.
Publicado: (2023)

Pharmacokinetics and Tissue Distribution Kinetics of Puerarin in Rats Using Indirect Competitive ELISA
por: Kong, Hui, et al.
Publicado: (2017)

Chronopharmacokinetics of Puerarin in Diabetic Rats
por: Zhang, C. T., et al.
Publicado: (2013)

Pharmacokinetic Comparison of Three Different Administration Routes for Topotecan Hydrochloride in Rats
por: Jeong, Seung-Hyun, et al.
Publicado: (2020)

A Novel Microspheres Formulation of Puerarin: Pharmacokinetics Study and In Vivo Pharmacodynamics Evaluations
por: Song, Xiao, et al.
Publicado: (2016)

Repeated Oral Administration of Human Serum Albumin Protects from the Cerebral Ischemia in Rat Brain Following MCAO
por: Park, Hyejin, et al.
Publicado: (2017)

LC-MS/MS determination and pharmacokinetics study of puerarin and daidzein in rat plasma after oral administration of Gegenqinlian decoction and Radix Puerariae extract
por: Zhang, Yifan, et al.
Publicado: (2014)

In vivo pharmacokinetic comparisons of ferulic acid and puerarin after oral administration of monomer, medicinal substance aqueous extract and Nao-De-Sheng to rats
por: Ouyang, Zhen, et al.
Publicado: (2012)

Global gene expression profile of cerebral ischemia-reperfusion injury in rat MCAO model
por: Wang, Chunmei, et al.
Publicado: (2017)

RNA-seq expression profiling of rat MCAO model following reperfusion Orexin-A
por: Wang, Chun-Mei, et al.
Publicado: (2017)

Enhancing Effect of Borneol and Muscone on Geniposide Transport across the Human Nasal Epithelial Cell Monolayer
por: Chen, Zhenzhen, et al.
Publicado: (2014)

In Situ and in Vivo Study of Nasal Absorption of Paeonol in Rats
por: Chen, Xiaolan, et al.
Publicado: (2010)

Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract
por: Xu, Zhan-Ling, et al.
Publicado: (2018)

Puerarin ameliorates allodynia and hyperalgesia in rats with peripheral nerve injury
por: Xie, Heng-Tao, et al.
Publicado: (2018)

Rapid Characterization of Components in Bolbostemma paniculatum by UPLC/LTQ-Orbitrap MS(n) Analysis and Multivariate Statistical Analysis for Herb Discrimination
por: Zeng, Yanling, et al.
Publicado: (2018)

The Effects and Possible Mechanisms of Puerarin to Treat Endometriosis Model Rats
por: Yu, Jin, et al.
Publicado: (2015)

Protective effect of puerarin against burn-induced heart injury in rats
por: Liu, Junling, et al.
Publicado: (2020)

A UPLC-ESI-MS/MS Method for Simultaneous Quantitation of Chlorogenic Acid, Scutellarin, and Scutellarein in Rat Plasma: Application to a Comparative Pharmacokinetic Study in Sham-Operated and MCAO Rats after Oral Administration of Erigeron breviscapus Extract
por: Chen, Siying, et al.
Publicado: (2018)

Puerarin ameliorated the behavioral deficits induced by chronic stress in rats
por: Qiu, Zhi-Kun, et al.
Publicado: (2017)

Puerarin transport across rat nasal epithelial cells and the influence of compatibility with peoniflorin and menthol
por: Zhang, Lin, et al.
Publicado: (2017)

Molecular Mechanism of Puerarin Against Diabetes and its Complications
por: Bai, Yi-ling, et al.
Publicado: (2022)

A study of optimal concentration range and time window of sevoflurane preconditioning for brain protection in MCAO rats
por: Deng, Ying, et al.
Publicado: (2020)

Bioevaluation of Pheretima vulgaris Antithrombotic Extract, PvQ, and Isolation, Identification of Six Novel PvQ-Derived Fibrinolytic Proteases
por: Yang, Wanqing, et al.
Publicado: (2021)

The Effects of Puerarin on Rat Ventricular Myocytes and the Potential Mechanism
por: Xu, Hao, et al.
Publicado: (2016)

Tracking Transplanted Bone Marrow Stem Cells and Their Effects in the Rat MCAO Stroke Model
por: Goldmacher, Gregory V., et al.
Publicado: (2013)

Spatiotemporal Protein Atlas of Cell Death-Related Molecules in the Rat MCAO Stroke Model
por: Yoon, Jeong Seon, et al.
Publicado: (2018)

Effects of Puerarin Combined with PLGA/TCP/Puerarin on Osteocalcin and Sialoprotein of Mandibular Defects
por: Guo, Ying, et al.
Publicado: (2022)

Pharmacokinetics and binding of the bioreductive probe for hypoxia, NITP: effect of route of administration.
por: Hodgkiss, R. J., et al.
Publicado: (1995)

A Comprehensive Review of Treprostinil Pharmacokinetics via Four Routes of Administration
por: Kumar, Parag, et al.
Publicado: (2016)

Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks
por: Wang, Chengtan, et al.
Publicado: (2021)

A Novel Fibrinolytic Protein From Pheretima vulgaris: Purification, Identification, Antithrombotic Evaluation, and Mechanisms Investigation
por: Liu, Hai, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a25is7ul1a6luhmkr01hnc7qad