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Buformin suppresses osteosarcoma via targeting AMPK signaling pathway

BACKGROUND: Buformin has been reported to be a powerful anticancer drug by activating the AMPK signal. Herein, we aimed to investigate the effects of buformin on osteosarcoma. MATERIAL AND METHODS: Cellular proliferative abilities were determined by cell counting kit-8 and colony formation assays. C...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Lv, Shiqiao, Li, Guangrun, Cui, Jinpeng, Chen, Yunzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874575/
https://www.ncbi.nlm.nih.gov/pubmed/33817229
http://dx.doi.org/10.1515/biol-2020-0041