Cargando…
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis
BACKGROUND: Homeobox A10 (HOXA10) belongs to the HOX gene family, which plays an essential role in embryonic development and tumor progression. We previously demonstrated that HOXA10 was significantly upregulated in gastric cancer (GC) and promoted GC cell proliferation. This study was designed to i...
Autores principales: | Song, Chenlong, Zhou, Chongzhi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874610/ https://www.ncbi.nlm.nih.gov/pubmed/33563300 http://dx.doi.org/10.1186/s13046-021-01859-0 |
Ejemplares similares
-
METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer
por: Yue, Ben, et al.
Publicado: (2019) -
Elevated HOXA13 expression promotes the proliferation and metastasis of gastric cancer partly via activating Erk1/2
por: Qin, Zhiwei, et al.
Publicado: (2019) -
HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer
por: Song, Chenlong, et al.
Publicado: (2019) -
Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1
por: Yuan, Chenwei, et al.
Publicado: (2016) -
HOXA13 promotes gastric cancer progression partially via the FN1-mediated FAK/Src axis
por: Qin, Zhiwei, et al.
Publicado: (2022)