New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs

Antiarrhythmic drugs are widely used, however, their efficacy is moderate and they can have serious side effects. Even if catheter ablation is effective for the treatment of atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs are still important tools for the treatment of arrhythmi...

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Detalles Bibliográficos
Autores principales: An, Zhe, Yang, Guang, Liu, Xuanxuan, Zhang, Zhongfan, Liu, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2018
Materias:
Topical Issue on Precision Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874705/
https://www.ncbi.nlm.nih.gov/pubmed/33817101
http://dx.doi.org/10.1515/biol-2018-0041
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author An, Zhe
Yang, Guang
Liu, Xuanxuan
Zhang, Zhongfan
Liu, Guohui
author_facet An, Zhe
Yang, Guang
Liu, Xuanxuan
Zhang, Zhongfan
Liu, Guohui
author_sort An, Zhe
collection PubMed
description Antiarrhythmic drugs are widely used, however, their efficacy is moderate and they can have serious side effects. Even if catheter ablation is effective for the treatment of atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs are still important tools for the treatment of arrhythmia. Despite efforts, the development of antiarrhythmic drugs is still slow due to the limited understanding of the role of various ionic currents. This review summarizes the new targets and mechanisms of antiarrhythmic drugs.
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spelling pubmed-78747052021-04-01 New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs An, Zhe Yang, Guang Liu, Xuanxuan Zhang, Zhongfan Liu, Guohui Open Life Sci Topical Issue on Precision Medicine Antiarrhythmic drugs are widely used, however, their efficacy is moderate and they can have serious side effects. Even if catheter ablation is effective for the treatment of atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs are still important tools for the treatment of arrhythmia. Despite efforts, the development of antiarrhythmic drugs is still slow due to the limited understanding of the role of various ionic currents. This review summarizes the new targets and mechanisms of antiarrhythmic drugs. De Gruyter 2018-09-22 /pmc/articles/PMC7874705/ /pubmed/33817101 http://dx.doi.org/10.1515/biol-2018-0041 Text en © 2018 Zhe An et al., published by De Gruyter http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
spellingShingle Topical Issue on Precision Medicine
An, Zhe
Yang, Guang
Liu, Xuanxuan
Zhang, Zhongfan
Liu, Guohui
New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs
title New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs
title_full New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs
title_fullStr New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs
title_full_unstemmed New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs
title_short New Progress in Understanding the Cellular Mechanisms of Anti-arrhythmic Drugs
title_sort new progress in understanding the cellular mechanisms of anti-arrhythmic drugs
topic Topical Issue on Precision Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874705/
https://www.ncbi.nlm.nih.gov/pubmed/33817101
http://dx.doi.org/10.1515/biol-2018-0041
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