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Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules

Nanoparticles have many applications both in industry and medicine. Depending upon their physical and chemical properties, they can be used as carriers of therapeutic molecules or as therapeutics. Nanoparticles are made of synthetic or natural polymers, lipids or metals. Their use allows for faster...

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Detalles Bibliográficos
Autores principales: Pudlarz, Agnieszka, Szemraj, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874720/
https://www.ncbi.nlm.nih.gov/pubmed/33817095
http://dx.doi.org/10.1515/biol-2018-0035
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author Pudlarz, Agnieszka
Szemraj, Janusz
author_facet Pudlarz, Agnieszka
Szemraj, Janusz
author_sort Pudlarz, Agnieszka
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description Nanoparticles have many applications both in industry and medicine. Depending upon their physical and chemical properties, they can be used as carriers of therapeutic molecules or as therapeutics. Nanoparticles are made of synthetic or natural polymers, lipids or metals. Their use allows for faster transport to the place of action, thus prolonging its presence in the body and limiting side effects. In addition, the use of such a drug delivery system protects the drug from rapid disintegration and elimination from the body. In recent years, the use of proteins and peptides as therapeutic molecules has grown significantly. Unfortunately, proteins are subject to enzymatic digestion and can cause unwanted immune response beyond therapeutic action. The use of drug carriers can minimize undesirable side effects and reduce the dose of medication needed to achieve the therapeutic effect. The current study presents the use of several selected drug delivery systems for the delivery of proteins, peptides and other therapeutic molecules.
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spelling pubmed-78747202021-04-01 Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules Pudlarz, Agnieszka Szemraj, Janusz Open Life Sci Review Article Nanoparticles have many applications both in industry and medicine. Depending upon their physical and chemical properties, they can be used as carriers of therapeutic molecules or as therapeutics. Nanoparticles are made of synthetic or natural polymers, lipids or metals. Their use allows for faster transport to the place of action, thus prolonging its presence in the body and limiting side effects. In addition, the use of such a drug delivery system protects the drug from rapid disintegration and elimination from the body. In recent years, the use of proteins and peptides as therapeutic molecules has grown significantly. Unfortunately, proteins are subject to enzymatic digestion and can cause unwanted immune response beyond therapeutic action. The use of drug carriers can minimize undesirable side effects and reduce the dose of medication needed to achieve the therapeutic effect. The current study presents the use of several selected drug delivery systems for the delivery of proteins, peptides and other therapeutic molecules. De Gruyter 2018-10-31 /pmc/articles/PMC7874720/ /pubmed/33817095 http://dx.doi.org/10.1515/biol-2018-0035 Text en © 2018 Agnieszka Pudlarz, Janusz Szemraj, published by De Gruyter http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
spellingShingle Review Article
Pudlarz, Agnieszka
Szemraj, Janusz
Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules
title Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules
title_full Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules
title_fullStr Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules
title_full_unstemmed Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules
title_short Nanoparticles as Carriers of Proteins, Peptides and Other Therapeutic Molecules
title_sort nanoparticles as carriers of proteins, peptides and other therapeutic molecules
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874720/
https://www.ncbi.nlm.nih.gov/pubmed/33817095
http://dx.doi.org/10.1515/biol-2018-0035
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