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Lactate Overload Inhibits Myogenic Activity in C2C12 Myotubes

Lactate (LA), an endogenous metabolite produced from pyruvate, can accumulate in skeletal muscle in certain conditions including major diseases, as well as during intensive exercise. Using differentiated C2C12 myotubes, we evaluated the early (1-h) and delayed (24-h) effects of LA (8 mM) on mechanis...

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Detalles Bibliográficos
Autores principales: Oh, Sarah Se-Jung, Kim, Sujin, Moon, Sohee, Park, Dong-Ho, Kang, Ju-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874767/
https://www.ncbi.nlm.nih.gov/pubmed/33817134
http://dx.doi.org/10.1515/biol-2019-0004