Cargando…

Nuciferine Prevents Hepatic Steatosis by Regulating Lipid Metabolismin Diabetic Rat Model

OBJECTIVE: This study investigatesthe nuciferine capacity to regulate the liver’s lipid metabolism regarding steatosis and injury in STZ-induced diabetic rats. MATERIALS AND METHODS: The rats were randomly divided into groups control, diabetic and nuciferine 200 mg/kg/ day treatment. After 4 days of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ning, Qian, Wang, Yang, Zhang, Yi, Shen, Guozhi, Xie, Zhenglu, Pang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874802/ https://www.ncbi.nlm.nih.gov/pubmed/33817209 http://dx.doi.org/10.1515/biol-2019-0079

Ejemplares similares

Nuciferine Prevents Hepatic Steatosis and Injury Induced by a High-Fat Diet in Hamsters
por: Guo, Fuchuan, et al.
Publicado: (2013)

Nuciferine reduced fat deposition by controlling triglyceride and cholesterol concentration in broiler chickens
por: Zhou, Yingying, et al.
Publicado: (2020)

Nuciferine modulates the gut microbiota and prevents obesity in high-fat diet-fed rats
por: Wang, Yu, et al.
Publicado: (2020)

Distinct AMPK-Mediated FAS/HSL Pathway Is Implicated in the Alleviating Effect of Nuciferine on Obesity and Hepatic Steatosis in HFD-Fed Mice
por: Xu, Hanyuan, et al.
Publicado: (2022)

Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy–lysosomal pathway
por: Du, Xiliang, et al.
Publicado: (2022)

Curcumin alleviates liver oxidative stress in type 1 diabetic rats
por: Xie, Zhenglu, et al.
Publicado: (2018)

In Vitro and In Vivo Characterization of the Alkaloid Nuciferine
por: Farrell, Martilias S., et al.
Publicado: (2016)

Preparation of microgel co-loaded with nuciferine and epigallocatechin-3-gallate for the regulation of lipid metabolism
por: Zhu, Shengnan, et al.
Publicado: (2022)

Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG(2) cells
por: Zhang, Dan-Dan, et al.
Publicado: (2015)

Study on the vasodilatory activity of lotus leaf extract and its representative substance nuciferine on thoracic aorta in rats
por: Deng, Hao, et al.
Publicado: (2022)

Protective Effects of Nuciferine in Middle Cerebral Artery Occlusion Rats Based on Transcriptomics
por: Chen, Chang, et al.
Publicado: (2022)

Exercise and spirulina control non-alcoholic hepatic steatosis and lipid profile in diabetic Wistar rats
por: Moura, Leandro P, et al.
Publicado: (2011)

Anti-Alzheimer and Antioxidant Effects of Nelumbo nucifera L. Alkaloids, Nuciferine and Norcoclaurine in Alloxan-Induced Diabetic Albino Rats
por: Khan, Shahnaz, et al.
Publicado: (2022)

Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease
por: Cui, Huantian, et al.
Publicado: (2020)

Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway
por: Xie, Ji-Rong, et al.
Publicado: (2023)

Nuciferine Regulates Immune Function and Gut Microbiota in DSS-Induced Ulcerative Colitis
por: Zhu, Yiling, et al.
Publicado: (2022)

Consumption of Spinach and Tomato Modifies Lipid Metabolism, Reducing Hepatic Steatosis in Rats
por: Elvira-Torales, Laura Inés, et al.
Publicado: (2020)

Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury
por: Zhou, Zixiong, et al.
Publicado: (2023)

Nuciferine Inhibited the Differentiation and Lipid Accumulation of 3T3-L1 Preadipocytes by Regulating the Expression of Lipogenic Genes and Adipokines
por: Xu, Hanyuan, et al.
Publicado: (2021)

Pharmacokinetics of Nuciferine and N-Nornuciferine, Two Major Alkaloids From Nelumbo nucifera Leaves, in Rat Plasma and the Brain
por: Ye, Lin-Hu, et al.
Publicado: (2018)

Processing tactics for low-cost production of pure nuciferine from lotus leaf
por: Ruan, Yeqing, et al.
Publicado: (2022)

Granulocyte Colony Stimulating Factor Ameliorates Hepatic Steatosis Associated with Improvement of Autophagy in Diabetic Rats
por: Joo, Hyun-Woo, et al.
Publicado: (2020)

Influence of Genistein on Hepatic Lipid Metabolism in an In Vitro Model of Hepatic Steatosis
por: Seidemann, Lena, et al.
Publicado: (2021)

Blackcurrant (Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats
por: Nanashima, Naoki, et al.
Publicado: (2020)

Preventive Effect of Nuciferine on H(2)O(2)-Induced Fibroblast Senescence and Pro-Inflammatory Cytokine Gene Expression
por: Charoensin, Suphachai, et al.
Publicado: (2022)

Ketogenic Essential Amino Acids Modulate Lipid Synthetic Pathways and Prevent Hepatic Steatosis in Mice
por: Noguchi, Yasushi, et al.
Publicado: (2010)

circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis
por: Guo, Xing-Ya, et al.
Publicado: (2017)

YAP Inhibition by Nuciferine via AMPK-Mediated Downregulation of HMGCR Sensitizes Pancreatic Cancer Cells to Gemcitabine
por: Zhou, Ling, et al.
Publicado: (2019)

UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals the Anti-Ischemic Stroke Mechanism of Nuciferine in MCAO Rats
por: Wu, Lanlan, et al.
Publicado: (2020)

PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies
por: Liu, Ying, et al.
Publicado: (2017)

Molecular docking study of nuciferine as a tyrosinase inhibitor and its therapeutic potential for hyperpigmentation
por: Veerichetty, Veerabhuvaneshwari, et al.
Publicado: (2023)

Strawberry, Blueberry, and Strawberry-Blueberry Blend Beverages Prevent Hepatic Steatosis in Obese Rats by Modulating Key Genes Involved in Lipid Metabolism
por: Sotelo-González, Ana María, et al.
Publicado: (2023)

Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides
por: Li, Yanmei, et al.
Publicado: (2017)

The liver steatosis severity and lipid characteristics in primary biliary cholangitis
por: Zhang, Yuan, et al.
Publicado: (2021)

Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist
por: Chan, John D., et al.
Publicado: (2016)

Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264.7 Cells
por: Zhang, Chao, et al.
Publicado: (2018)

Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis
por: BasuRay, Soumik, et al.
Publicado: (2019)

Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats
por: Qin, Ying, et al.
Publicado: (2010)

Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway
por: Cho, In-Jin, et al.
Publicado: (2021)

Role of Patatin-Like Phospholipase Domain-Containing 3 on Lipid-Induced Hepatic Steatosis and Insulin Resistance in Rats
por: Kumashiro, Naoki, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2njmvcudpgb6ui7v2lt8vsg28t