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Nurr1 Promotes Lung Cancer Apoptosis Via Enhancing Mitochondrial Stress and p53-Drp1 Pathway

OBJECTIVE: Mitochondrial homeostasis is vital for the progression of lung cancer. Nurr1 has been identified as a novel mediator of mitochondrial homeostasis in several types of cancers. The aim of our study was to investigate whether Nurr1 modulates the viability of A549 lung cancer cells by inducin...

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Detalles Bibliográficos
Autores principales: Zhao, Shu, Li, Peng, Wang, Peng, Yang, Jing, Song, Peng, Zhang, Dong, Zhou, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874811/
https://www.ncbi.nlm.nih.gov/pubmed/33817160
http://dx.doi.org/10.1515/biol-2019-0030