Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19

COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response variation to disease severity and outcome over time, we longitudinally assessed circulating proteins as well as 188 surface protein markers, transcriptome, and T cell receptor sequence simultaneously in single peri...

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Detalles Bibliográficos
Autores principales: Liu, Can, Martins, Andrew J., Lau, William W., Rachmaninoff, Nicholas, Chen, Jinguo, Imberti, Luisa, Mostaghimi, Darius, Fink, Danielle L., Burbelo, Peter D., Dobbs, Kerry, Delmonte, Ottavia M., Bansal, Neha, Failla, Laura, Sottini, Alessandra, Quiros-Roldan, Eugenia, Han, Kyu Lee, Sellers, Brian A., Cheung, Foo, Sparks, Rachel, Chun, Tae-Wook, Moir, Susan, Lionakis, Michail S., Rossi, Camillo, Su, Helen C., Kuhns, Douglas B., Cohen, Jeffrey I., Notarangelo, Luigi D., Tsang, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874909/
https://www.ncbi.nlm.nih.gov/pubmed/33713619
http://dx.doi.org/10.1016/j.cell.2021.02.018

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