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Immunologic goalposts for TB vaccine development
A limiting factor in identifying effective tuberculosis (TB) vaccines is our incomplete understanding of correlates of protection. In this issue of Cell Host & Microbe, Esaulova et al. reveal cell types associated with TB containment and disease progression in non-human primates, which may provi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874915/ https://www.ncbi.nlm.nih.gov/pubmed/33571443 http://dx.doi.org/10.1016/j.chom.2021.01.011 |
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author | Um, Peter K. Bishai, William R. |
author_facet | Um, Peter K. Bishai, William R. |
author_sort | Um, Peter K. |
collection | PubMed |
description | A limiting factor in identifying effective tuberculosis (TB) vaccines is our incomplete understanding of correlates of protection. In this issue of Cell Host & Microbe, Esaulova et al. reveal cell types associated with TB containment and disease progression in non-human primates, which may provide immunologic goalposts for vaccine design. |
format | Online Article Text |
id | pubmed-7874915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78749152021-02-11 Immunologic goalposts for TB vaccine development Um, Peter K. Bishai, William R. Cell Host Microbe In Translation A limiting factor in identifying effective tuberculosis (TB) vaccines is our incomplete understanding of correlates of protection. In this issue of Cell Host & Microbe, Esaulova et al. reveal cell types associated with TB containment and disease progression in non-human primates, which may provide immunologic goalposts for vaccine design. Elsevier Inc. 2021-02-10 2021-02-10 /pmc/articles/PMC7874915/ /pubmed/33571443 http://dx.doi.org/10.1016/j.chom.2021.01.011 Text en © 2021 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | In Translation Um, Peter K. Bishai, William R. Immunologic goalposts for TB vaccine development |
title | Immunologic goalposts for TB vaccine development |
title_full | Immunologic goalposts for TB vaccine development |
title_fullStr | Immunologic goalposts for TB vaccine development |
title_full_unstemmed | Immunologic goalposts for TB vaccine development |
title_short | Immunologic goalposts for TB vaccine development |
title_sort | immunologic goalposts for tb vaccine development |
topic | In Translation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7874915/ https://www.ncbi.nlm.nih.gov/pubmed/33571443 http://dx.doi.org/10.1016/j.chom.2021.01.011 |
work_keys_str_mv | AT umpeterk immunologicgoalpostsfortbvaccinedevelopment AT bishaiwilliamr immunologicgoalpostsfortbvaccinedevelopment |