Development and Characterization of PLGA Nanoparticle-Laden Hydrogels for Sustained Ocular Delivery of Norfloxacin in the Treatment of Pseudomonas Keratitis: An Experimental Study

AIM: Norfloxacin (NFX) has low ocular bioavailability. The current work aimed to develop NFX-loaded nanoparticle (NP)-laden hydrogels to improve the ocular potential of NFX, minimize the need for frequent instillations and lower undesirable side effects. METHODS: NFX-loaded NPs were developed via th...

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Detalles Bibliográficos
Autores principales: Gebreel, Rana M, Edris, Noha A, Elmofty, Hala M, Tadros, Mina I, El-Nabarawi, Mohamed A, Hassan, Doaa H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875077/
https://www.ncbi.nlm.nih.gov/pubmed/33584095
http://dx.doi.org/10.2147/DDDT.S293127

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