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PTEN Promoter Hypermethylation Is Associated with Breslow Thickness in Acral Melanoma on the Heel, Forefoot, and Hallux

BACKGROUND: Acral melanoma occurs on glabrous skin or the nail apparatus and is distinct from ultraviolet-related melanoma due to differing genetic alteration patterns. Although the pathogenesis of acral melanoma is not well understood, mechanical stress is thought to induce acral melanoma. The inci...

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Detalles Bibliográficos
Autores principales: Park, Hae Seok, Kim, Jong Hoon, Cho, Mi Yeon, Chung, Kee Yang, Roh, Mi Ryung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875221/
https://www.ncbi.nlm.nih.gov/pubmed/33911808
http://dx.doi.org/10.5021/ad.2021.33.1.18

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