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Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations

Adolescent idiopathic scoliosis, is a three-dimensional spinal deformity characterized by lateral curvature and axial rotation around the vertical body axis of the spine, the cause of which is yet unknown. The fast progression entails regular clinical monitoring, including X-rays. Here we present an...

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Autores principales: Grünwald, Alexander T. D., Roy, Susmita, Alves-Pinto, Ana, Lampe, Renée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875351/
https://www.ncbi.nlm.nih.gov/pubmed/33566808
http://dx.doi.org/10.1371/journal.pone.0243736
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author Grünwald, Alexander T. D.
Roy, Susmita
Alves-Pinto, Ana
Lampe, Renée
author_facet Grünwald, Alexander T. D.
Roy, Susmita
Alves-Pinto, Ana
Lampe, Renée
author_sort Grünwald, Alexander T. D.
collection PubMed
description Adolescent idiopathic scoliosis, is a three-dimensional spinal deformity characterized by lateral curvature and axial rotation around the vertical body axis of the spine, the cause of which is yet unknown. The fast progression entails regular clinical monitoring, including X-rays. Here we present an approach to evaluate scoliosis from the three-dimensional image of a patient’s torso, captured by an ionizing radiation free body scanner, in combination with a model of the ribcage and spine. A skeletal structure of the ribcage and vertebral column was modelled with computer aided designed software and was used as an initial structure for macroscopic finite element method simulations. The basic vertebral column model was created for an adult female in an upright position. The model was then used to simulate the patient specific scoliotic spine configurations. The simulations showed that a lateral translation of a vertebral body results in an effective axial rotation and could reproduce the spinal curvatures. The combined method of three-dimensional body scan and finite element model simulations thus provide quantitative anatomical information about the position, rotation and inclination of the thoracic and lumbar vertebrae within a three-dimensional torso. Furthermore, the simulations showed unequal distributions of stress and strain profiles across the intervertebral discs, due to their distortions, which might help to further understand the pathogenesis of scoliosis.
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spelling pubmed-78753512021-02-19 Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations Grünwald, Alexander T. D. Roy, Susmita Alves-Pinto, Ana Lampe, Renée PLoS One Research Article Adolescent idiopathic scoliosis, is a three-dimensional spinal deformity characterized by lateral curvature and axial rotation around the vertical body axis of the spine, the cause of which is yet unknown. The fast progression entails regular clinical monitoring, including X-rays. Here we present an approach to evaluate scoliosis from the three-dimensional image of a patient’s torso, captured by an ionizing radiation free body scanner, in combination with a model of the ribcage and spine. A skeletal structure of the ribcage and vertebral column was modelled with computer aided designed software and was used as an initial structure for macroscopic finite element method simulations. The basic vertebral column model was created for an adult female in an upright position. The model was then used to simulate the patient specific scoliotic spine configurations. The simulations showed that a lateral translation of a vertebral body results in an effective axial rotation and could reproduce the spinal curvatures. The combined method of three-dimensional body scan and finite element model simulations thus provide quantitative anatomical information about the position, rotation and inclination of the thoracic and lumbar vertebrae within a three-dimensional torso. Furthermore, the simulations showed unequal distributions of stress and strain profiles across the intervertebral discs, due to their distortions, which might help to further understand the pathogenesis of scoliosis. Public Library of Science 2021-02-10 /pmc/articles/PMC7875351/ /pubmed/33566808 http://dx.doi.org/10.1371/journal.pone.0243736 Text en © 2021 Grünwald et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Grünwald, Alexander T. D.
Roy, Susmita
Alves-Pinto, Ana
Lampe, Renée
Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
title Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
title_full Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
title_fullStr Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
title_full_unstemmed Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
title_short Assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
title_sort assessment of adolescent idiopathic scoliosis from body scanner image by finite element simulations
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875351/
https://www.ncbi.nlm.nih.gov/pubmed/33566808
http://dx.doi.org/10.1371/journal.pone.0243736
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