Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments

Filoviruses, such as the Ebola virus (EBOV) and Marburg virus (MARV), are causative agents of sporadic outbreaks of hemorrhagic fevers in humans. To infect cells, filoviruses are internalized via macropinocytosis and traffic through the endosomal pathway where host cathepsin-dependent cleavage of th...

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Detalles Bibliográficos
Autores principales: Stewart, Corina M., Phan, Alexandra, Bo, Yuxia, LeBlond, Nicholas D., Smith, Tyler K. T., Laroche, Geneviève, Giguère, Patrick M., Fullerton, Morgan D., Pelchat, Martin, Kobasa, Darwyn, Côté, Marceline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875390/
https://www.ncbi.nlm.nih.gov/pubmed/33513206
http://dx.doi.org/10.1371/journal.ppat.1009275

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