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Estimating the time-varying reproduction number of COVID-19 with a state-space method
After slowing down the spread of the novel coronavirus COVID-19, many countries have started to relax their confinement measures in the face of critical damage to socioeconomic structures. At this stage, it is desirable to monitor the degree to which political measures or social affairs have exerted...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875393/ https://www.ncbi.nlm.nih.gov/pubmed/33513137 http://dx.doi.org/10.1371/journal.pcbi.1008679 |
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author | Koyama, Shinsuke Horie, Taiki Shinomoto, Shigeru |
author_facet | Koyama, Shinsuke Horie, Taiki Shinomoto, Shigeru |
author_sort | Koyama, Shinsuke |
collection | PubMed |
description | After slowing down the spread of the novel coronavirus COVID-19, many countries have started to relax their confinement measures in the face of critical damage to socioeconomic structures. At this stage, it is desirable to monitor the degree to which political measures or social affairs have exerted influence on the spread of disease. Though it is difficult to trace back individual transmission of infections whose incubation periods are long and highly variable, estimating the average spreading rate is possible if a proper mathematical model can be devised to analyze daily event-occurrences. To render an accurate assessment, we have devised a state-space method for fitting a discrete-time variant of the Hawkes process to a given dataset of daily confirmed cases. The proposed method detects changes occurring in each country and assesses the impact of social events in terms of the temporally varying reproduction number, which corresponds to the average number of cases directly caused by a single infected case. Moreover, the proposed method can be used to predict the possible consequences of alternative political measures. This information can serve as a reference for behavioral guidelines that should be adopted according to the varying risk of infection. |
format | Online Article Text |
id | pubmed-7875393 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-78753932021-02-19 Estimating the time-varying reproduction number of COVID-19 with a state-space method Koyama, Shinsuke Horie, Taiki Shinomoto, Shigeru PLoS Comput Biol Research Article After slowing down the spread of the novel coronavirus COVID-19, many countries have started to relax their confinement measures in the face of critical damage to socioeconomic structures. At this stage, it is desirable to monitor the degree to which political measures or social affairs have exerted influence on the spread of disease. Though it is difficult to trace back individual transmission of infections whose incubation periods are long and highly variable, estimating the average spreading rate is possible if a proper mathematical model can be devised to analyze daily event-occurrences. To render an accurate assessment, we have devised a state-space method for fitting a discrete-time variant of the Hawkes process to a given dataset of daily confirmed cases. The proposed method detects changes occurring in each country and assesses the impact of social events in terms of the temporally varying reproduction number, which corresponds to the average number of cases directly caused by a single infected case. Moreover, the proposed method can be used to predict the possible consequences of alternative political measures. This information can serve as a reference for behavioral guidelines that should be adopted according to the varying risk of infection. Public Library of Science 2021-01-29 /pmc/articles/PMC7875393/ /pubmed/33513137 http://dx.doi.org/10.1371/journal.pcbi.1008679 Text en © 2021 Koyama et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Koyama, Shinsuke Horie, Taiki Shinomoto, Shigeru Estimating the time-varying reproduction number of COVID-19 with a state-space method |
title | Estimating the time-varying reproduction number of COVID-19 with a state-space method |
title_full | Estimating the time-varying reproduction number of COVID-19 with a state-space method |
title_fullStr | Estimating the time-varying reproduction number of COVID-19 with a state-space method |
title_full_unstemmed | Estimating the time-varying reproduction number of COVID-19 with a state-space method |
title_short | Estimating the time-varying reproduction number of COVID-19 with a state-space method |
title_sort | estimating the time-varying reproduction number of covid-19 with a state-space method |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875393/ https://www.ncbi.nlm.nih.gov/pubmed/33513137 http://dx.doi.org/10.1371/journal.pcbi.1008679 |
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