Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

The COVID-19 pandemic has revealed that infection with SARS-CoV-2 can result in a wide range of clinical outcomes in humans. An incomplete understanding of immune correlates of protection represents a major barrier to the design of vaccines and therapeutic approaches to prevent infection or limit di...

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Detalles Bibliográficos
Autores principales: Graham, Jessica B., Swarts, Jessica L., Leist, Sarah R., Schäfer, Alexandra, Menachery, Vineet D., Gralinski, Lisa E., Jeng, Sophia, Miller, Darla R., Mooney, Michael A., McWeeney, Shannon K., Ferris, Martin T., Pardo-Manuel de Villena, Fernando, Heise, Mark T., Baric, Ralph S., Lund, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875398/
https://www.ncbi.nlm.nih.gov/pubmed/33513210
http://dx.doi.org/10.1371/journal.ppat.1009287

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