Cargando…

Defining endogenous TACC3–chTOG–clathrin–GTSE1 interactions at the mitotic spindle using induced relocalization

A multiprotein complex containing TACC3, clathrin and other proteins has been implicated in mitotic spindle stability. To disrupt this complex in an anti-cancer context, we need to understand its composition and how it interacts with microtubules. Induced relocalization of proteins in cells is a pow...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryan, Ellis L., Shelford, James, Massam-Wu, Teresa, Bayliss, Richard, Royle, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875487/ https://www.ncbi.nlm.nih.gov/pubmed/33380489 http://dx.doi.org/10.1242/jcs.255794

Ejemplares similares

Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding
por: Hood, Fiona E., et al.
Publicado: (2013)

chTOG is a conserved mitotic error correction factor
por: Herman, Jacob A, et al.
Publicado: (2020)

TACC3–ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
por: Gutiérrez-Caballero, Cristina, et al.
Publicado: (2015)

Solution NMR assignment of the C-terminal domain of human chTOG
por: Rostkova, Elena, et al.
Publicado: (2018)

FGFR3–TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindle
por: Sarkar, Sourav, et al.
Publicado: (2017)

Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module
por: Roostalu, Johanna, et al.
Publicado: (2015)

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability
por: Lin, Chiou-Hong, et al.
Publicado: (2010)

TACC3–ch-TOG interaction regulates spindle microtubule assembly by controlling centrosomal recruitment of γ-TuRC
por: Rajeev, Resmi, et al.
Publicado: (2023)

Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly
por: Burgess, Selena G., et al.
Publicado: (2015)

Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix
por: Burgess, Selena G, et al.
Publicado: (2018)

Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability
por: Tan, Shengjiang, et al.
Publicado: (2008)

Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG
por: Foraker, Amy B., et al.
Publicado: (2012)

TOG–tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation
por: Byrnes, Amy E., et al.
Publicado: (2017)

CDK-dependent phosphorylation of Alp7–Alp14 (TACC–TOG) promotes its nuclear accumulation and spindle microtubule assembly
por: Okada, Naoyuki, et al.
Publicado: (2014)

Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast
por: Tang, Ngang Heok, et al.
Publicado: (2014)

Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism
por: Hussmann, Frauke, et al.
Publicado: (2016)

A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly
por: Barr, Alexis R., et al.
Publicado: (2015)

Erratum: A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly
por: Barr, Alexis R., et al.
Publicado: (2015)

ZYG-9(ch-TOG) promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis
por: Cavin-Meza, Gabriel, et al.
Publicado: (2022)

The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment
por: Tang, Ngang Heok, et al.
Publicado: (2013)

Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression
por: O’Regan, Laura, et al.
Publicado: (2015)

An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis
por: Kaur, Satdip, et al.
Publicado: (2014)

Eribulin targets a ch-TOG-dependent directed migration of cancer cells
por: Chanez, Brice, et al.
Publicado: (2015)

Sorting Nexin 9 Recruits Clathrin Heavy Chain to the Mitotic Spindle for Chromosome Alignment and Segregation
por: Ma, Maggie P. C., et al.
Publicado: (2013)

Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation
por: Zheng, Fan, et al.
Publicado: (2014)

Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG
por: Ali, Aamir, et al.
Publicado: (2023)

Clathrin Is Spindle-Associated but Not Essential for Mitosis
por: Borlido, Joana, et al.
Publicado: (2008)

Clathrin teams up to strengthen the spindle
por: Leslie, Mitch
Publicado: (2010)

GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms
por: Tipton, Aaron R., et al.
Publicado: (2017)

Structures of TOG1 and TOG2 from the human microtubule dynamics regulator CLASP1
por: Leano, Jonathan B., et al.
Publicado: (2019)

Aberrations of TACC1 and TACC3 are associated with ovarian cancer
por: Lauffart, Brenda, et al.
Publicado: (2005)

Concentrating on the mitotic spindle
por: Maddox, Paul S., et al.
Publicado: (2015)

Ndc80 Internal Loop Interacts with Dis1/TOG to Ensure Proper Kinetochore-Spindle Attachment in Fission Yeast
por: Hsu, Kuo-Shun, et al.
Publicado: (2011)

Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus
por: Messina, Giovanni, et al.
Publicado: (2022)

Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly
por: Ibarlucea-Benitez, Itziar, et al.
Publicado: (2018)

Force and the spindle: Mechanical cues in mitotic spindle orientation
por: Nestor-Bergmann, Alexander, et al.
Publicado: (2014)

ACTIN AND MYOSIN IN THE MITOTIC SPINDLE
por: Robinson, Richard
Publicado: (2008)

Cell division and the mitotic spindle
por: Inoue, S.
Publicado: (1981)

The TOG protein Stu2 is regulated by acetylation
por: Greenlee, Matt A., et al.
Publicado: (2022)

An unconventional TOG domain is required for CLASP localization
por: Gareil, Nelly, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_267k2mfh2m2qi1np7t5t3q650v