Cargando…
Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
Recognition of the adverse events of inferior vena cava filters (VCFs) has prompted the Food and Drug Administration (FDA) to issue safety warnings (2010 and 2014), advocating for removal, once the risk of pulmonary embolism has abated. Despite an initial increase in retrieval rates, these remain lo...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875678/ https://www.ncbi.nlm.nih.gov/pubmed/33585788 http://dx.doi.org/10.1055/s-0040-1722707 |
_version_ | 1783649809260871680 |
---|---|
author | Ionescu, Filip Anusim, Nwabundo Ma, Eva Qu, Lihua Blankenship, LeAnn M. Stender, Michael Jaiyesimi, Ishmael |
author_facet | Ionescu, Filip Anusim, Nwabundo Ma, Eva Qu, Lihua Blankenship, LeAnn M. Stender, Michael Jaiyesimi, Ishmael |
author_sort | Ionescu, Filip |
collection | PubMed |
description | Recognition of the adverse events of inferior vena cava filters (VCFs) has prompted the Food and Drug Administration (FDA) to issue safety warnings (2010 and 2014), advocating for removal, once the risk of pulmonary embolism has abated. Despite an initial increase in retrieval rates, these remain low (25–30% at 1 year in 2014). We retrospectively investigated retrieval trends in adults with VCFs placed between 2015 and 2018 at a single institution. The rate of retrievable VCF removal accounting for the competing risk of death was the main outcome. There were 494 VCFs placed (305 retrievable). The cumulative incidence of retrieval remained low (21% at 1 year), even after the second FDA warning (2014). Patients who resumed anticoagulation (AC) at any time were more likely to have retrieval (hazard ratio [HR] = 3.6, p < 0.01) and had higher retrieval rates at every time point (31.4 vs. 7.6% at 1 year). Advanced age (HR = 0.98 per year, p = 0.004), stroke (HR = 0.28, p = 0.028), and active malignancy (HR = 0.42, p = 0.006) predicted nonretrieval. Device-related complications were infrequent (<1%) but thrombotic complications occurred early and were more common for nonretrieved VCFs (17 vs. 12%, p = 0.29). Revision of guidelines to recommend active surveillance for the ability to tolerate AC in the immediate postimplantation period may improve retrieval rates. |
format | Online Article Text |
id | pubmed-7875678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-78756782021-02-12 Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience Ionescu, Filip Anusim, Nwabundo Ma, Eva Qu, Lihua Blankenship, LeAnn M. Stender, Michael Jaiyesimi, Ishmael TH Open Recognition of the adverse events of inferior vena cava filters (VCFs) has prompted the Food and Drug Administration (FDA) to issue safety warnings (2010 and 2014), advocating for removal, once the risk of pulmonary embolism has abated. Despite an initial increase in retrieval rates, these remain low (25–30% at 1 year in 2014). We retrospectively investigated retrieval trends in adults with VCFs placed between 2015 and 2018 at a single institution. The rate of retrievable VCF removal accounting for the competing risk of death was the main outcome. There were 494 VCFs placed (305 retrievable). The cumulative incidence of retrieval remained low (21% at 1 year), even after the second FDA warning (2014). Patients who resumed anticoagulation (AC) at any time were more likely to have retrieval (hazard ratio [HR] = 3.6, p < 0.01) and had higher retrieval rates at every time point (31.4 vs. 7.6% at 1 year). Advanced age (HR = 0.98 per year, p = 0.004), stroke (HR = 0.28, p = 0.028), and active malignancy (HR = 0.42, p = 0.006) predicted nonretrieval. Device-related complications were infrequent (<1%) but thrombotic complications occurred early and were more common for nonretrieved VCFs (17 vs. 12%, p = 0.29). Revision of guidelines to recommend active surveillance for the ability to tolerate AC in the immediate postimplantation period may improve retrieval rates. Georg Thieme Verlag KG 2021-02-10 /pmc/articles/PMC7875678/ /pubmed/33585788 http://dx.doi.org/10.1055/s-0040-1722707 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Ionescu, Filip Anusim, Nwabundo Ma, Eva Qu, Lihua Blankenship, LeAnn M. Stender, Michael Jaiyesimi, Ishmael Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience |
title | Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience |
title_full | Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience |
title_fullStr | Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience |
title_full_unstemmed | Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience |
title_short | Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience |
title_sort | inferior vena cava filter retrieval trends: a single-center experience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875678/ https://www.ncbi.nlm.nih.gov/pubmed/33585788 http://dx.doi.org/10.1055/s-0040-1722707 |
work_keys_str_mv | AT ionescufilip inferiorvenacavafilterretrievaltrendsasinglecenterexperience AT anusimnwabundo inferiorvenacavafilterretrievaltrendsasinglecenterexperience AT maeva inferiorvenacavafilterretrievaltrendsasinglecenterexperience AT qulihua inferiorvenacavafilterretrievaltrendsasinglecenterexperience AT blankenshipleannm inferiorvenacavafilterretrievaltrendsasinglecenterexperience AT stendermichael inferiorvenacavafilterretrievaltrendsasinglecenterexperience AT jaiyesimiishmael inferiorvenacavafilterretrievaltrendsasinglecenterexperience |