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Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience

Recognition of the adverse events of inferior vena cava filters (VCFs) has prompted the Food and Drug Administration (FDA) to issue safety warnings (2010 and 2014), advocating for removal, once the risk of pulmonary embolism has abated. Despite an initial increase in retrieval rates, these remain lo...

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Autores principales: Ionescu, Filip, Anusim, Nwabundo, Ma, Eva, Qu, Lihua, Blankenship, LeAnn M., Stender, Michael, Jaiyesimi, Ishmael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875678/
https://www.ncbi.nlm.nih.gov/pubmed/33585788
http://dx.doi.org/10.1055/s-0040-1722707
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author Ionescu, Filip
Anusim, Nwabundo
Ma, Eva
Qu, Lihua
Blankenship, LeAnn M.
Stender, Michael
Jaiyesimi, Ishmael
author_facet Ionescu, Filip
Anusim, Nwabundo
Ma, Eva
Qu, Lihua
Blankenship, LeAnn M.
Stender, Michael
Jaiyesimi, Ishmael
author_sort Ionescu, Filip
collection PubMed
description Recognition of the adverse events of inferior vena cava filters (VCFs) has prompted the Food and Drug Administration (FDA) to issue safety warnings (2010 and 2014), advocating for removal, once the risk of pulmonary embolism has abated. Despite an initial increase in retrieval rates, these remain low (25–30% at 1 year in 2014). We retrospectively investigated retrieval trends in adults with VCFs placed between 2015 and 2018 at a single institution. The rate of retrievable VCF removal accounting for the competing risk of death was the main outcome. There were 494 VCFs placed (305 retrievable). The cumulative incidence of retrieval remained low (21% at 1 year), even after the second FDA warning (2014). Patients who resumed anticoagulation (AC) at any time were more likely to have retrieval (hazard ratio [HR] = 3.6, p  < 0.01) and had higher retrieval rates at every time point (31.4 vs. 7.6% at 1 year). Advanced age (HR = 0.98 per year, p  = 0.004), stroke (HR = 0.28, p  = 0.028), and active malignancy (HR = 0.42, p  = 0.006) predicted nonretrieval. Device-related complications were infrequent (<1%) but thrombotic complications occurred early and were more common for nonretrieved VCFs (17 vs. 12%, p  = 0.29). Revision of guidelines to recommend active surveillance for the ability to tolerate AC in the immediate postimplantation period may improve retrieval rates.
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spelling pubmed-78756782021-02-12 Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience Ionescu, Filip Anusim, Nwabundo Ma, Eva Qu, Lihua Blankenship, LeAnn M. Stender, Michael Jaiyesimi, Ishmael TH Open Recognition of the adverse events of inferior vena cava filters (VCFs) has prompted the Food and Drug Administration (FDA) to issue safety warnings (2010 and 2014), advocating for removal, once the risk of pulmonary embolism has abated. Despite an initial increase in retrieval rates, these remain low (25–30% at 1 year in 2014). We retrospectively investigated retrieval trends in adults with VCFs placed between 2015 and 2018 at a single institution. The rate of retrievable VCF removal accounting for the competing risk of death was the main outcome. There were 494 VCFs placed (305 retrievable). The cumulative incidence of retrieval remained low (21% at 1 year), even after the second FDA warning (2014). Patients who resumed anticoagulation (AC) at any time were more likely to have retrieval (hazard ratio [HR] = 3.6, p  < 0.01) and had higher retrieval rates at every time point (31.4 vs. 7.6% at 1 year). Advanced age (HR = 0.98 per year, p  = 0.004), stroke (HR = 0.28, p  = 0.028), and active malignancy (HR = 0.42, p  = 0.006) predicted nonretrieval. Device-related complications were infrequent (<1%) but thrombotic complications occurred early and were more common for nonretrieved VCFs (17 vs. 12%, p  = 0.29). Revision of guidelines to recommend active surveillance for the ability to tolerate AC in the immediate postimplantation period may improve retrieval rates. Georg Thieme Verlag KG 2021-02-10 /pmc/articles/PMC7875678/ /pubmed/33585788 http://dx.doi.org/10.1055/s-0040-1722707 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Ionescu, Filip
Anusim, Nwabundo
Ma, Eva
Qu, Lihua
Blankenship, LeAnn M.
Stender, Michael
Jaiyesimi, Ishmael
Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
title Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
title_full Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
title_fullStr Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
title_full_unstemmed Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
title_short Inferior Vena Cava Filter Retrieval Trends: A Single-Center Experience
title_sort inferior vena cava filter retrieval trends: a single-center experience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875678/
https://www.ncbi.nlm.nih.gov/pubmed/33585788
http://dx.doi.org/10.1055/s-0040-1722707
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