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Microglial Hyperreactivity Evolved to Immunosuppression in the Hippocampus of a Mouse Model of Accelerated Aging and Alzheimer’s Disease Traits
Neuroinflammation is a risk factor for Alzheimer’s disease (AD). We sought to study the glial derangement in AD using diverse experimental models and human brain tissue. Besides classical pro-inflammatory cytokines, we analyzed chitinase 3 like 1 (CHI3L1 or YKL40) and triggering receptor expressed o...
Autores principales: | Molina-Martínez, Patricia, Corpas, Rubén, García-Lara, Elisa, Cosín-Tomás, Marta, Cristòfol, Rosa, Kaliman, Perla, Solà, Carme, Molinuevo, José Luis, Sánchez-Valle, Raquel, Antonell, Anna, Lladó, Albert, Sanfeliu, Coral |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875867/ https://www.ncbi.nlm.nih.gov/pubmed/33584248 http://dx.doi.org/10.3389/fnagi.2020.622360 |
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