Cargando…

Neuregulin‐1 alleviate oxidative stress and mitigate inflammation by suppressing NOX4 and NLRP3/caspase‐1 in myocardial ischaemia‐reperfusion injury

Neuregulin‐1 (NRG‐1) is reported to be cardioprotective through the extracellular‐regulated protein kinase (ERK) 1/2 pathway in myocardial ischaemia‐reperfusion injury (MIRI). NOX4‐induced ROS activated NLRP3 inflammasome and exacerbates MIRI. This study aims to investigate whether NRG‐1 can suppres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Fuhua, Wang, Huan, Liu, Xuejing, Yu, Haiyi, Huang, Xiaomin, Huang, Wei, Wang, Guisong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875921/ https://www.ncbi.nlm.nih.gov/pubmed/33470533 http://dx.doi.org/10.1111/jcmm.16287

Ejemplares similares

Pharmacological postconditioning with Neuregulin-1 mimics the cardioprotective effects of ischaemic postconditioning via ErbB4-dependent activation of reperfusion injury salvage kinase pathway
por: Wang, Fuhua, et al.
Publicado: (2018)

Selenium nanoparticles alleviate ischemia reperfusion injury-induced acute kidney injury by modulating GPx-1/NLRP3/Caspase-1 pathway
por: Wang, Shaobo, et al.
Publicado: (2022)

Maternal diabetes up‐regulates NOX2 and enhances myocardial ischaemia/reperfusion injury in adult offspring
por: Zhang, Lili, et al.
Publicado: (2018)

Dexmedetomidine alleviates hepatic ischaemia‐reperfusion injury via the PI3K/AKT/Nrf2‐NLRP3 pathway
por: Wu, Yan, et al.
Publicado: (2021)

Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation
por: Wang, Yaqiong, et al.
Publicado: (2016)

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
por: Sokolovska, Anna, et al.
Publicado: (2013)

Immunoproteasome modulates NLRP3 inflammasome‐mediated neuroinflammation under cerebral ischaemia and reperfusion conditions
por: Chen, Xingyong, et al.
Publicado: (2021)

Ginsenoside Rh2 attenuates myocardial ischaemia‑reperfusion injury by regulating the Nrf2/HO‑1/NLRP3 signalling pathway
por: Fan, Zhi-Xing, et al.
Publicado: (2022)

Itaconic acid facilitates inflammation abatement and alleviates liver ischemia-reperfusion injury by inhibiting NF-κB/NLRP3/caspase-1 inflammasome axis
por: Ma, Ensi, et al.
Publicado: (2022)

The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice
por: Cui, Yu, et al.
Publicado: (2018)

Machine perfusion of the liver: Which is the best technique to mitigate ischaemia-reperfusion injury?
por: Boteon, Yuri L, et al.
Publicado: (2019)

Therapeutic hypothermia alleviates myocardial ischaemia–reperfusion injury by inhibiting inflammation and fibrosis via the mediation of the SIRT3/NLRP3 signalling pathway
por: Zhang, Jing, et al.
Publicado: (2022)

NLRX1/FUNDC1/NIPSNAP1‐2 axis regulates mitophagy and alleviates intestinal ischaemia/reperfusion injury
por: Li, Shaoqin, et al.
Publicado: (2021)

Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2‐related programmed cell death in an AMPK‐dependent manner
por: Wang, Chunyan, et al.
Publicado: (2020)

Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway
por: Wang, Kangyu, et al.
Publicado: (2023)

Isoflurane Attenuates Cerebral Ischaemia–Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice
por: Zhang, Ya-Jun, et al.
Publicado: (2022)

YTHDF1 alleviates sepsis by upregulating WWP1 to induce NLRP3 ubiquitination and inhibit caspase-1-dependent pyroptosis
por: Zhang, Shuyao, et al.
Publicado: (2022)

Alteration of serum neuregulin 4 and neuregulin 1 in gestational diabetes mellitus
por: Zhang, Lei, et al.
Publicado: (2021)

Baicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro
por: Li, Yanyan, et al.
Publicado: (2022)

Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway
por: Wu, Chan, et al.
Publicado: (2022)

Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury
por: Baidya, Raji, et al.
Publicado: (2020)

Treadmill training mitigates bone deterioration via inhibiting NLRP3/Caspase1/IL-1β signaling in aged rats
por: Wu, Qi, et al.
Publicado: (2022)

Neuregulin 1 Expression and Electrophysiological Abnormalities in the Neuregulin 1 Transmembrane Domain Heterozygous Mutant Mouse
por: Long, Leonora E., et al.
Publicado: (2015)

miRNA-146a Mimic Inhibits NOX4/P38 Signalling to Ameliorate Mouse Myocardial Ischaemia Reperfusion (I/R) Injury
por: Xiao, Lili, et al.
Publicado: (2021)

Inhibition of TIM‐4 protects against cerebral ischaemia‐reperfusion injury
por: Zheng, Lifang, et al.
Publicado: (2019)

Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1
por: Wang, Jun, et al.
Publicado: (2020)

Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury
por: Shi, Chengyu, et al.
Publicado: (2020)

Purinergic neurotransmission receptor P2X4 silencing alleviates intracerebral hemorrhage-induced neuroinflammation by blocking the NLRP1/Caspase-1 pathway
por: Wu, Yuanshui, et al.
Publicado: (2023)

Therapeutic effects of neuregulin-1 in diabetic cardiomyopathy rats
por: Li, Bingong, et al.
Publicado: (2011)

Danshensu alleviates cardiac ischaemia/reperfusion injury by inhibiting autophagy and apoptosis via activation of mTOR signalling
por: Fan, Guanwei, et al.
Publicado: (2016)

Ellagic acid Alleviates hepatic ischemia–reperfusion injury in C57 mice via the Caspase-1-GSDMD pathway
por: Wang, Hao, et al.
Publicado: (2022)

Dietary Curcumin Alleviated Aflatoxin B1-Induced Acute Liver Damage in Ducks by Regulating NLRP3–Caspase-1 Signaling Pathways
por: Jin, Sanjun, et al.
Publicado: (2021)

Theacrine alleviates sepsis-induced acute kidney injury by repressing the activation of NLRP3/Caspase-1 inflammasome
por: Yang, Maoxian, et al.
Publicado: (2022)

Complement in ischaemia–reperfusion injury and transplantation
por: Howard, Mark C., et al.
Publicado: (2021)

Curcumin inhibits cerebral ischaemia–reperfusion injury and cell apoptosis in rats through the ERK–CHOP–caspase-11 pathway
por: Chen, Yue, et al.
Publicado: (2022)

BACE1-Dependent Neuregulin-1 Signaling: An Implication for Schizophrenia
por: Zhang, Zhengrong, et al.
Publicado: (2017)

Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury
por: Afolabi, O. A., et al.
Publicado: (2022)

Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury
por: Rusiecka, Olga M, et al.
Publicado: (2023)

Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis
por: Zhang, Yueting, et al.
Publicado: (2022)

SIRT1 alleviates hepatic ischemia-reperfusion injury via the miR-182-mediated XBP1/NLRP3 pathway
por: Li, Fengwei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d15f0hbq0j0d7ah75adbnrg155