Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation

Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are two distinct autoimmune diseases that manifest with chronic synovial inflammation. Here, we show that CD4(+) T cells from patients with RA and PsA have increased expression of the pore-forming calcium channel component ORAI3, thereby increa...

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Detalles Bibliográficos
Autores principales: Ye, Zhongde, Shen, Yi, Jin, Ke, Qiu, Jingtao, Hu, Bin, Jadhav, Rohit R., Sheth, Khushboo, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875984/
https://www.ncbi.nlm.nih.gov/pubmed/33568645
http://dx.doi.org/10.1038/s41467-021-21242-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875984/
https://www.ncbi.nlm.nih.gov/pubmed/33568645
http://dx.doi.org/10.1038/s41467-021-21242-z

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