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Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression
Glutathione (GSH) is an important antioxidant that plays a critical role in neuroprotection. GSH depletion in neurons induces oxidative stress and thereby promotes neuronal damage, which in turn is regarded as a hallmark of the early stage of neurodegenerative diseases. The neuronal GSH level is mai...
Autores principales: | Kinoshita, Chisato, Kikuchi-Utsumi, Kazue, Aoyama, Koji, Suzuki, Ryo, Okamoto, Yayoi, Matsumura, Nobuko, Omata, Daiki, Maruyama, Kazuo, Nakaki, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876013/ https://www.ncbi.nlm.nih.gov/pubmed/33568779 http://dx.doi.org/10.1038/s42003-021-01706-0 |
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