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T(FH) Cells Induced by Vaccination and Following SIV Challenge Support Env-Specific Humoral Immunity in the Rectal-Genital Tract and Circulation of Female Rhesus Macaques
T follicular helper (T(FH)) cells are pivotal in lymph node (LN) germinal center (GC) B cell affinity maturation. Circulating CXCR5(+) CD4(+) T (cT(FH)) cells have supported memory B cell activation and broadly neutralizing antibodies in HIV controllers. We investigated the contribution of LN SIV-sp...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876074/ https://www.ncbi.nlm.nih.gov/pubmed/33584682 http://dx.doi.org/10.3389/fimmu.2020.608003 |