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High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility
Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. HPV is epitheliotropic and its replication is tightly associated with terminal keratinocyte differentiation making production and purification of high titer virus preparations for research problemat...
Autores principales: | Goetschius, Daniel J., Hartmann, Samantha R., Subramanian, Suriyasri, Bator, Carol M., Christensen, Neil D., Hafenstein, Susan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876116/ https://www.ncbi.nlm.nih.gov/pubmed/33568731 http://dx.doi.org/10.1038/s41598-021-83076-5 |
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