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IP3R1 regulates Ca(2+) transport and pyroptosis through the NLRP3/Caspase-1 pathway in myocardial ischemia/reperfusion injury

Intracellular ion channel inositol 1,4,5-triphosphate receptor (IP3R1) releases Ca(2+) from endoplasmic reticulum. The disturbance of IP3R1 is related to several neurodegenerative diseases. This study investigated the mechanism of IP3R1 in myocardial ischemia/reperfusion (MI/R). After MI/R modeling,...

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Detalles Bibliográficos
Autores principales:	Mo, Guixi, Liu, Xin, Zhong, Yiyue, Mo, Jian, Li, Zhiyi, Li, Daheng, Zhang, Liangqing, Liu, Yijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876122/ https://www.ncbi.nlm.nih.gov/pubmed/33568649 http://dx.doi.org/10.1038/s41420-021-00404-4

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