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A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
The global impact of somatic structural variants (SSVs) on gene expression in pediatric brain tumors has not been thoroughly characterised. Here, using whole-genome and RNA sequencing from 854 tumors of more than 30 different types from the Children’s Brain Tumor Tissue Consortium, we report the alt...
Autores principales: | Zhang, Yiqun, Chen, Fengju, Donehower, Lawrence A., Scheurer, Michael E., Creighton, Chad J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876141/ https://www.ncbi.nlm.nih.gov/pubmed/33568653 http://dx.doi.org/10.1038/s41467-021-21081-y |
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