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The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
α-Synuclein (αS) is a presynaptic disordered protein whose aberrant aggregation is associated with Parkinson’s disease. The functional role of αS is still debated, although it has been involved in the regulation of neurotransmitter release via the interaction with synaptic vesicles (SVs). We report...
Autores principales: | Man, Wing K., Tahirbegi, Bogachan, Vrettas, Michail D., Preet, Swapan, Ying, Liming, Vendruscolo, Michele, De Simone, Alfonso, Fusco, Giuliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876145/ https://www.ncbi.nlm.nih.gov/pubmed/33568632 http://dx.doi.org/10.1038/s41467-021-21027-4 |
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