Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype

Global dysregulation of RNA splicing and imbalanced sphingolipid metabolism has emerged as promoters of cancer cell transformation. Here, we present specific signature of alternative splicing (AS) events of sphingolipid genes for each breast cancer subtype from the TCGA-BRCA dataset. We show that ce...

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Detalles Bibliográficos
Autores principales: Pani, Trishna, Rajput, Kajal, Kar, Animesh, Sharma, Harsh, Basak, Rituparna, Medatwal, Nihal, Saha, Sandhini, Dev, Gagan, Kumar, Sharwan, Gupta, Siddhi, Mukhopadhyay, Arnab, Malakar, Dipankar, Maiti, Tushar Kanti, Arimbasseri, Aneeshkumar G., Deo, S. V. S., Sharma, Ravi Datta, Bajaj, Avinash, Dasgupta, Ujjaini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876150/
https://www.ncbi.nlm.nih.gov/pubmed/33568634
http://dx.doi.org/10.1038/s41419-021-03436-x

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