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The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae
The anti-CD20 antibody Rituximab to deplete CD20+ B cells is an effective treatment for rheumatoid arthritis and B cell malignancies, but is associated with an increased incidence of respiratory infections. Using mouse models we have investigated the consequences of B cell depletion on natural and a...
Autores principales: | Ercoli, Giuseppe, Ramos-Sevillano, Elisa, Nakajima, Rie, de Assis, Rafael Ramiro, Jasinskas, Algis, Goldblatt, David, Felgner, Philip, Weckbecker, Gisbert, Brown, Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876223/ https://www.ncbi.nlm.nih.gov/pubmed/33584691 http://dx.doi.org/10.3389/fimmu.2020.611661 |
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