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Shedding of Klotho: Functional Implications in Chronic Kidney Disease and Associated Vascular Disease

α-Klotho (Klotho) exists in two different forms, a membrane-bound and soluble form, which are highly expressed in the kidney. Both forms play an important role in various physiological and pathophysiological processes. Recently, it has been identified that soluble Klotho arises exclusively from shed...

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Detalles Bibliográficos
Autores principales: Saar-Kovrov, Valeria, Donners, Marjo M. P. C., van der Vorst, Emiel P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876272/
https://www.ncbi.nlm.nih.gov/pubmed/33585584
http://dx.doi.org/10.3389/fcvm.2020.617842