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Exosomal Long Non-coding RNA HOTTIP Increases Resistance of Colorectal Cancer Cells to Mitomycin via Impairing MiR-214-Mediated Degradation of KPNA3

It has been reported that long non-coding RNA HOXA distal transcript antisense RNA (lncRNA HOTTIP) functions as a tumor promoter in colorectal cancer (CRC). Hence, we paid attention to exploring whether exosomes could carry lncRNA HOTTIP to affect the mitomycin resistance in CRC and to identify the...

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Detalles Bibliográficos
Autores principales:	Chen, Xijuan, Liu, Yingqiang, Zhang, Qinglan, Liu, Baoxing, Cheng, Yan, Zhang, Yonglei, Sun, Yanan, Liu, Junqi, Gen, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876302/ https://www.ncbi.nlm.nih.gov/pubmed/33585440 http://dx.doi.org/10.3389/fcell.2020.582723

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