Hypoxia in Cell Reprogramming and the Epigenetic Regulations

Cellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal. Other factor...

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Detalles Bibliográficos
Autores principales: Nakamura, Nariaki, Shi, Xiaobing, Darabi, Radbod, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876330/
https://www.ncbi.nlm.nih.gov/pubmed/33585477
http://dx.doi.org/10.3389/fcell.2021.609984
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author Nakamura, Nariaki
Shi, Xiaobing
Darabi, Radbod
Li, Yong
author_facet Nakamura, Nariaki
Shi, Xiaobing
Darabi, Radbod
Li, Yong
author_sort Nakamura, Nariaki
collection PubMed
description Cellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal. Other factors involved during development include hypoxia and epigenetics, which play major roles in the development of tissues and organs. This review will discuss the involvement of hypoxia and epigenetics in the regulation of cellular reprogramming and how interplay between each factor can contribute to different cellular functions as well as tissue regeneration.
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spelling pubmed-78763302021-02-12 Hypoxia in Cell Reprogramming and the Epigenetic Regulations Nakamura, Nariaki Shi, Xiaobing Darabi, Radbod Li, Yong Front Cell Dev Biol Cell and Developmental Biology Cellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal. Other factors involved during development include hypoxia and epigenetics, which play major roles in the development of tissues and organs. This review will discuss the involvement of hypoxia and epigenetics in the regulation of cellular reprogramming and how interplay between each factor can contribute to different cellular functions as well as tissue regeneration. Frontiers Media S.A. 2021-01-28 /pmc/articles/PMC7876330/ /pubmed/33585477 http://dx.doi.org/10.3389/fcell.2021.609984 Text en Copyright © 2021 Nakamura, Shi, Darabi and Li. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Nakamura, Nariaki
Shi, Xiaobing
Darabi, Radbod
Li, Yong
Hypoxia in Cell Reprogramming and the Epigenetic Regulations
title Hypoxia in Cell Reprogramming and the Epigenetic Regulations
title_full Hypoxia in Cell Reprogramming and the Epigenetic Regulations
title_fullStr Hypoxia in Cell Reprogramming and the Epigenetic Regulations
title_full_unstemmed Hypoxia in Cell Reprogramming and the Epigenetic Regulations
title_short Hypoxia in Cell Reprogramming and the Epigenetic Regulations
title_sort hypoxia in cell reprogramming and the epigenetic regulations
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876330/
https://www.ncbi.nlm.nih.gov/pubmed/33585477
http://dx.doi.org/10.3389/fcell.2021.609984
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